Evidence map›Paper›PMID 36012953›Full record

ArticleJournal of clinical medicine2022

Frailty Assessed with FRAIL Scale and G8 Questionnaire Predicts Severe Postoperative Complications in Patients Receiving Major Head and Neck Surgery.

Viktor Kunz, Gunnar Wichmann, Theresa Wald, Markus Pirlich, Veit Zebralla, Andreas Dietz, Susanne Wiegand

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Viktor KunzDepartment of Otolaryngology, Head and Neck Surgery, University Hospital Leipzig, 04103 Leipzig, Germany.
Gunnar WichmannDepartment of Otolaryngology, Head and Neck Surgery, University Hospital Leipzig, 04103 Leipzig, Germany.ORCID 0000-0001-6191-2095
Theresa WaldDepartment of Otolaryngology, Head and Neck Surgery, University Hospital Leipzig, 04103 Leipzig, Germany.ORCID 0000-0002-7602-1743
Markus PirlichDepartment of Otolaryngology, Head and Neck Surgery, University Hospital Leipzig, 04103 Leipzig, Germany.
Veit ZebrallaDepartment of Otolaryngology, Head and Neck Surgery, University Hospital Leipzig, 04103 Leipzig, Germany.ORCID 0000-0001-5519-7566
Andreas DietzDepartment of Otolaryngology, Head and Neck Surgery, University Hospital Leipzig, 04103 Leipzig, Germany.
Susanne WiegandDepartment of Otolaryngology, Head and Neck Surgery, University Hospital Leipzig, 04103 Leipzig, Germany.
University Hospital Leipzig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFrailty represents a complex geriatric syndrome associated with elevated rates of postoperative complications as shown for several malignant entities, including head and neck cancer. A specific screening instrument to assess frailty in head and neck patients does not exist. Both the FRAIL Scale and the G8 questionnaire are well-established and easy to use as screening tools. The present study's aim was to assess the potential of frailty screening to predict postoperative complications in head and neck patients prior to surgery. PATIENTS AND

methodsWe recorded demographic data, pre-existing medical conditions and clinical characteristics in a prospective cohort of 104 head and neck cancer patients undergoing major head and neck surgery and assessed frailty prospectively on the day of admission utilizing the G8 questionnaire and the FRAIL Scale. We analyzed the link between occurrence of postoperative complications up to the twenty-first postoperative day and age, frailty and other covariates using χ

resultsThere was no significant correlation between patients' pre-existing medical conditions and postoperative complications. Whereas chronological age alone did not predict the occurrence of postoperative complications, frailty posed the highest risk for complications. Frailty according to either the G8 questionnaire or the FRAIL Scale predicted occurrence of complications with an area under the curve (AUC) of 0.64 (

conclusionProspective screening using the FRAIL Scale or the G8 questionnaire reliably detected frailty in our sample group. Frailty is linked to increased risk of postoperative complications. The correct prediction of severe postoperative complications as shown identifies vulnerable cases and triggers awareness of potential complications. Anticipating risk allows for a more comprehensive view of the patient and triggers decision making towards risk adjustment, and therefore a selective view of alternative treatment modalities.

Indexed as

FRAIL ScalefrailtyG8 questionnairehead and neck cancerhead and neck squamous cell carcinomahead and neck surgerypostoperative complications

Identifiers

PMID36012953
PMCPMC9409964
OpenAlexW4291885897

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.