ArticleJournal of clinical medicine2022
Epilepsy in Pediatric Patients-Evaluation of Brain Structures' Volume Using VolBrain Software.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Brain Volume Alterations and Cognitive Functions in Patients with Common Variable Immunodeficiency: Evaluating the Impact of Autoimmunity.Journal of clinical medicine · 2026Article
- Subcortical volume alteration and correlation with social function under chlorpromazine versus clozapine treatment in schizophrenia.BMC psychiatry · 2025Article
- Measurement of Limbic System Anatomical Volumes in Patients Diagnosed with Schizophrenia Using Vol2brain and Comparison with Healthy Individuals.Medicina (Kaunas, Lithuania) · 2025Article
- Age-related volume decrease in subcortical gray matter is a part of healthy brain aging in men.Irish journal of medical science · 2025Article
- Selective correlation of hippocampal volumes with WADA memory scores in mesial temporal sclerosis patients.Frontiers in neurology · 2025Article
- Developing a machine learning model to assist in predicting treatment success in children with drug-resistant epilepsy.Frontiers in neurology · 2025Article
- A Comparison of Pre- and Post-Treatment Cranial MRI Characteristics in Patients with Pediatric Epilepsy Receiving Levetiracetam.Medicina (Kaunas, Lithuania) · 2024Article
- Somatostatin interneuron fate-mapping and structure in a Pten knockout model of epilepsy.Frontiers in cellular neuroscience · 2024Article
- Valproate associated brain volume-loss in pediatric epilepsy-A case series.Epilepsia open · 2023Article
- Chiari 1 Malformation and Epilepsy in Children: A Missing Relationship.Journal of clinical medicine · 2022Article
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Authors and funding
11 authors.
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Abstract
Epilepsy is one of the most frequent serious brain disorders. Approximately 30,000 of the 150,000 children and adolescents who experience unprovoked seizures are diagnosed with epilepsy each year. Magnetic resonance imaging is the method of choice in diagnosing and monitoring patients with this condition. However, one very effective tool using MR images is volBrain software, which automatically generates information about the volume of brain structures. A total of 57 consecutive patients (study group) suffering from epilepsy and 34 healthy patients (control group) who underwent MR examination qualified for the study. Images were then evaluated by volBrain. Results showed atrophy of the brain and particular structures-GM, cerebrum, cerebellum, brainstem, putamen, thalamus, hippocampus and nucleus accumbens volume. Moreover, the statistically significant difference in the volume between the study and the control group was found for brain, lateral ventricle and putamen. A volumetric analysis of the CNS in children with epilepsy confirms a decrease in the volume of brain tissue. A volumetric assessment of brain structures based on MR data has the potential to be a useful diagnostic tool in children with epilepsy and can be implemented in clinical work; however, further studies are necessary to enhance the effectiveness of this software.
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