Evidence map›Paper›PMID 36012881›Full record

ArticleJournal of clinical medicine2022

Vasospasm-Related Death after Aneurysmal Subarachnoid Hemorrhage: A Retrospective Case-Control Study.

Ali Khanafer, Pervinder Bhogal, Victoria Hellstern, Christoph Harmening, Hansjörg Bäzner, Oliver Ganslandt, Hans Henkes

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ali KhanaferNeuroradiological Clinic, Klinikum Stuttgart, D-70174 Stuttgart, Germany.
Pervinder BhogalInterventional Neuroradiology Department, The Royal London Hospital, Barts NHS Trust, London E1 1FR, UK.
Victoria HellsternNeuroradiological Clinic, Klinikum Stuttgart, D-70174 Stuttgart, Germany.
Christoph HarmeningClinic for Anesthesiology and Surgical Intensive Care Medicine, Klinikum Stuttgart, D-70174 Stuttgart, Germany.
Hansjörg BäznerNeurological Clinic, Klinikum Stuttgart, D-70174 Stuttgart, Germany.ORCID 0000-0001-8944-8239
Oliver GanslandtNeurosurgical Clinic, Klinikum Stuttgart, D-70174 Stuttgart, Germany.
Hans HenkesNeuroradiological Clinic, Klinikum Stuttgart, D-70174 Stuttgart, Germany.ORCID 0000-0002-6534-036X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVasospasm after the rupture of an intracranial aneurysm is a frequent phenomenon and is the main cause of morbidity and mortality in patients who have survived intracranial hemorrhage and aneurysm treatment. We analyzed the diagnosis and management of patients with aneurysmal subarachnoid hemorrhage who eventually died from ischemic brain damage due to vasospasm.

methodsBetween January 2007 and December 2021 (15 years), a total of 1064 patients were diagnosed with an aneurysmal intracranial hemorrhage in a single comprehensive neurovascular center. Vasospasm was diagnosed in 408 patients (38.4%). A total of 187 patients (17.6%) died within 90 days of the aneurysm rupture. In 64 of these 187 patients (33.7%), vasospasm was considered to be the cause of death. In a retrospective analysis, demographic and clinical data for patients without, with non-fatal, and with fatal vasospasm were compared. The patients with fatal vasospasm were categorized into the following subgroups: "no diagnosis and treatment" (Group a), "delayed diagnosis" (Group b), "cardiovascular complications" (Group c), and "vasospasm-treatment complications" (Group d).

resultsAmong the patients with fatal vasospasm, 31 (48.4%) were assigned to group a, 26 (40.6%) to group b, seven (10.9%) to group c, and none (0%) to group d.

conclusionThe early recognition of severe posthemorrhagic vasospasm is a prerequisite for any treatment and requires routine diagnostic imaging in all unconscious patients. Aggressive endovascular vasospasm treatment may fail to prevent death but is infrequently the cause of a fatal outcome.

Indexed as

cerebral vasospasmendovascular treatmentintracranial aneurysmsubarachnoid hemorrhage

Identifiers

PMID36012881
PMCPMC9410410

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.