Evidence map›Paper›PMID 36012832›Full record

ArticleJournal of fungi (Basel, Switzerland)2022

Diagnostic Performance and Clinical Utility of Conventional PCR Assay in Early Diagnosis of COVID-19 Associated Rhino-Orbito-Cerebral Mucormycosis.

Samir Mohapatra, Manas Ranjan Barik, Suryasnata Rath, Savitri Sharma, Archisman Mohapatra, Sharmistha Behera, Souvagini Acharya, Dipti Ranjan Pattjoshi, Rajesh Kumar Padhi, Himansu Sekhar Behera

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Current Issues in Fungal Infections and COVID-19.Journal of fungi (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Samir MohapatraDepartment of Ophthalmic Plastic and Reconstructive Surgery Service, L V Prasad Eye Institute, Mithu Tulsi Chanrai Campus, Bhubaneswar 751024, Odisha, India.
Manas Ranjan BarikOcular Microbiology Service, L V Prasad Eye Institute, Mithu Tulsi Chanrai Campus, Bhubaneswar 751024, Odisha, India.
Suryasnata RathDepartment of Ophthalmic Plastic and Reconstructive Surgery Service, L V Prasad Eye Institute, Mithu Tulsi Chanrai Campus, Bhubaneswar 751024, Odisha, India.
Savitri SharmaJhaveri Microbiology Centre, L V Prasad Eye Institute, Kallam Anji Reddy Campus, Hyderabad 500034, Telangana, India.ORCID 0000-0001-9979-264X
Archisman MohapatraDepartment of Biostatistics, Generating Research Insights for Development (GRID) Council, Noida 201307, Delhi NCR, India.
Sharmistha BeheraDepartment of Ophthalmology, VSSIMSAR, Burla 768017, Odisha, India.ORCID 0000-0003-1861-6113
Souvagini AcharyaDepartment of Ear, Nose and Throat, VSSIMSAR, Burla 768017, Odisha, India.ORCID 0000-0003-3580-0211
Dipti Ranjan PattjoshiDepartment of Ear, Nose and Throat, SCB Medical College and Hospital, Cuttack 753007, Odisha, India.
Rajesh Kumar PadhiDepartment of Ear, Nose and Throat, Sparsh Hospitals Pvt Ltd., Bhubaneswar 751007, Odisha, India.
Himansu Sekhar BeheraOcular Microbiology Service, L V Prasad Eye Institute, Mithu Tulsi Chanrai Campus, Bhubaneswar 751024, Odisha, India.ORCID 0000-0003-4638-2836
L V Prasad Eye Institute · INVeer Surendra Sai University of Technology · INSparsh Hospital · INSriram Chandra Bhanja Medical College Hospital · IN

Funding

mgm 12321
6 · The paper itself

Abstract

Early diagnosis and treatment of rhino-orbital-cerebral mucormycosis (ROCM) are crucial. Potassium hydroxide with Calcofluorwhite (KOH + CFW) smears can demonstrate the fungal hyphae, but mixed infections caused by both mucorales and non-mucorales pose a diagnostic challenge. Polymerase chain reaction (PCR) can detect mixed infections and differentiate mucorales from non-mucorales. This study aimed to evaluate the utility of a single reaction PCR in the diagnosis of ROCM and the efficacy of nasal biopsy and endonasal swab in the detection of fungus.

Indexed as

endonasal swabsKOH + CFW smearmixed infectionmucormycosisnasal biopsyPCR assay

Identifiers

PMID36012832
PMCPMC9409716
OpenAlexW4291008784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.