Evidence map›Paper›PMID 36012800›Full record

ReviewJournal of fungi (Basel, Switzerland)2022

Emerging Trends in the Use of Topical Antifungal-Corticosteroid Combinations.

Dalibor Mijaljica, Fabrizio Spada, Ian P Harrison

Open access · goldAbstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Antifungal Dispensing in Denmark: Patterns Across Primary Care, Secondary Care, and Over-the-Counter Sectors.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026
    Article
  2. Pharmacological assessment of drugs retained in the 1Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Article
  3. Article
  4. Dermatophytoses Caused byJournal of fungi (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Caffeine Protects Keratinocytes fromInternational journal of molecular sciences · 2024
    Article
  7. Article
  8. Journal of clinical medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dalibor MijaljicaDepartment of Scientific Affairs, Ego Pharmaceuticals Pty Ltd., 21-31 Malcolm Road, Braeside, VIC 3195, Australia.ORCID 0000-0002-8519-286X
Fabrizio SpadaDepartment of Scientific Affairs, Ego Pharmaceuticals Pty Ltd., 21-31 Malcolm Road, Braeside, VIC 3195, Australia.ORCID 0000-0002-3324-6301
Ian P HarrisonDepartment of Scientific Affairs, Ego Pharmaceuticals Pty Ltd., 21-31 Malcolm Road, Braeside, VIC 3195, Australia.ORCID 0000-0002-5269-5823

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A broad range of topical antifungal formulations containing miconazole or terbinafine as actives are commonly used as efficacious choices for combating fungal skin infections. Their many benefits, owing to their specific mechanism of action, include their ability to target the site of infection, enhance treatment efficacy and reduce the risk of systemic side effects. Their proven efficacy, and positioning in the treatment of fungal skin infections, is enhanced by high patient compliance, especially when appropriate vehicles such as creams, ointments and gels are used. However, inflammation as a result of fungal infection can often impede treatment, especially when combined with pruritus (itch), an unpleasant sensation that elicits an urge to scratch. The scratching that occurs in response to pruritus frequently accelerates skin damage, ultimately aggravating and spreading the fungal infection. To help overcome this issue, a topical antifungal-corticosteroid combination consisting of miconazole or terbinafine and corticosteroids of varying potencies should be used. Due to their inherent benefits, these topical antifungal-corticosteroid combinations can concomitantly and competently attenuate inflammation, relieve pruritus and treat fungal infection.

Indexed as

allylaminesazolesergosterolformulationfungiinfectioninflammationitchmiconazoleskinterbinafine

Identifiers

PMID36012800
PMCPMC9409645
OpenAlexW4289344411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.