Evidence map›Paper›PMID 36012727›Full record

ArticleInternational journal of molecular sciences2022

Toxic and Phenotypic Effects of AAV_Cre Used to Transduce Mesencephalic Dopaminergic Neurons.

Larissa Erben, Jacqueline P Welday, Ricardo Murphy, Andres Buonanno

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Gene therapy for neurotransmitter-related disorders.Journal of inherited metabolic disease · 2024
    Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Larissa ErbenSection on Molecular Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Jacqueline P WeldaySection on Molecular Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0003-0151-7418
Ricardo MurphySection on Molecular Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-3452-3438
Andres BuonannoSection on Molecular Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
National Institutes of Health · US

Funding

Neuregulin-ErbB Signaling in Neuronal Development and Psychiatric DisordersZIAHD000711 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI BUONANNO, ANDRES · 2009 to 2024
$24.4M
Eunice Kennedy Shriver National Institute of Child Health and Human Development ZIA-HD000711Intramural NIH HHS ZIA HD000711
6 · The paper itself

Abstract

A popular approach to spatiotemporally target genes using the

Indexed as

DependovirusDopaminergic NeuronsTransduction, GeneticAnimalsIntegrasesMiceReceptor, ErbB-4Tyrosine 3-MonooxygenaseCre recombinaseIntegrasesReceptor, ErbB-4Tyrosine 3-Monooxygenaseadeno-associated virusCre recombinasedopaminestereotaxic injectiontoxicitytyrosine hydroxylaseventral tegmental area

Identifiers

PMID36012727
PMCPMC9408874
OpenAlexW4293515028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.