Evidence map›Paper›PMID 36012699›Full record

ArticleInternational journal of molecular sciences2022

Vascular Reactions of the Diving Reflex in Men and Women Carrying Different ADRA1A Genotypes.

Tatyana Baranova, Ekaterina Podyacheva, Tatyana Zemlyanukhina, Dmitrii Berlov, Maria Danilova, Oleg Glotov, Andrey Glotov

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Molecular Mechanisms of Adaptation to Hypoxia.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Tatyana BaranovaFaculty of Biology, Saint Petersburg State University, 199034 Saint-Petersburg, Russia.
Ekaterina PodyachevaFaculty of Biology, Saint Petersburg State University, 199034 Saint-Petersburg, Russia.
Tatyana ZemlyanukhinaFaculty of Biology, Saint Petersburg State University, 199034 Saint-Petersburg, Russia.
Dmitrii BerlovFaculty of Biology, Herzen State Pedagogical University of Russia, 191186 Saint-Petersburg, Russia.
Maria DanilovaDepartment of Genomic Medicine, D.O. Ott's Institute of Obstetrics, Gynecology and Reproductology, 199034 Saint-Petersburg, Russia.
Oleg GlotovDepartment of Genomic Medicine, D.O. Ott's Institute of Obstetrics, Gynecology and Reproductology, 199034 Saint-Petersburg, Russia.ORCID 0000-0002-0091-2224
Andrey GlotovDepartment of Genomic Medicine, D.O. Ott's Institute of Obstetrics, Gynecology and Reproductology, 199034 Saint-Petersburg, Russia.ORCID 0000-0002-7465-4504
Research Institute of Obstetrics and Gynecology named after D.O. Ott · RUSt Petersburg University · RUHerzen University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diving reflex is an oxygen-saving mechanism which is accompanied by apnea, reflex bradycardia development, peripheral vasoconstriction, spleen erythrocyte release, and selective redistribution of blood flow to the organs most vulnerable to lack of oxygen, such as the brain, heart, and lungs. However, this is a poorly studied form of hypoxia, with a knowledge gap on physiological and biochemical adaptation mechanisms. The reflective sympathetic constriction of the resistive vessels is realized via ADRA1A. It has been shown that ADRA1A SNP (

Indexed as

Diving ReflexReceptors, Adrenergic, alpha-1AdolescentAdultApneaBradycardiaFemaleGenotypeHeart RateHumansHypoxiaMaleOxygenYoung AdultADRA1A protein, humanOxygenReceptors, Adrenergic, alpha-1diving reflexpolymorphism Arg347 ADRA1A (rs1048101)pulmonary blood flowpulmonary vascular tonesexual dimorphism in humanvasoconstrictionvasodilation

Identifiers

PMID36012699
PMCPMC9409260
OpenAlexW4293679850

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.