Evidence map›Paper›PMID 36012643›Full record

ReviewInternational journal of molecular sciences2022

Role of Ion Channels in the Chemotransduction and Mechanotransduction in Digestive Function and Feeding Behavior.

Zhenya Zhu, Yuhao Wu, Ziyu Liu, Yuezhou Li, Mizu Jiang

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Piezo channels in tumors.Journal of cancer research and clinical oncology · 2026
    Review
  3. Review
  4. Piezo channels in the intestinal tract.Frontiers in physiology · 2024
    Review
  5. Piezo1 in Digestive System Function and Dysfunction.International journal of molecular sciences · 2023
    Review
  6. Review
  7. Effects of Dietary Sodium Nitroprusside and NAnimals : an open access journal from MDPI · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhenya ZhuEndoscopy Center and Gastrointestinal Laboratory, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou 310052, China.ORCID 0000-0003-4843-5540
Yuhao WuEndoscopy Center and Gastrointestinal Laboratory, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou 310052, China.
Ziyu LiuEndoscopy Center and Gastrointestinal Laboratory, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou 310052, China.
Yuezhou LiNational Health Center and Chinese Academy of Medical Sciences Key Laboratory of Medical Neurobiology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou 310052, China.
Mizu JiangEndoscopy Center and Gastrointestinal Laboratory, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou 310052, China.ORCID 0000-0003-4829-2041

Funding

Key Research, Development Project of Zhejiang Province 2021C03064project from the National Clinical Research Center for Child Health G20A0008
6 · The paper itself

Abstract

The gastrointestinal tract constantly communicates with the environment, receiving and processing a wide range of information. The contents of the gastrointestinal tract and the gastrointestinal tract generate mechanical and chemical signals, which are essential for regulating digestive function and feeding behavior. There are many receptors here that sense intestinal contents, including nutrients, microbes, hormones, and small molecule compounds. In signal transduction, ion channels are indispensable as an essential component that can generate intracellular ionic changes or electrical signals. Ion channels generate electrical activity in numerous neurons and, more importantly, alter the action of non-neurons simply and effectively, and also affect satiety, molecular secretion, intestinal secretion, and motility through mechanisms of peripheral sensation, signaling, and altered cellular function. In this review, we focus on the identity of ion channels in chemosensing and mechanosensing in the gastrointestinal tract.

Indexed as

Ion ChannelsMechanotransduction, CellularFeeding BehaviorGastrointestinal TractIonsSignal TransductionIon ChannelsIonschemical stimulationion channelsmechanical stimulationsignaling transduction

Identifiers

PMID36012643
PMCPMC9409042

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.