Evidence map›Paper›PMID 36012615›Full record

ArticleInternational journal of molecular sciences2022

Combined Treatment of Bronchial Epithelial Calu-3 Cells with Peptide Nucleic Acids Targeting miR-145-5p and miR-101-3p: Synergistic Enhancement of the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (

Chiara Papi, Jessica Gasparello, Matteo Zurlo, Alex Manicardi, Roberto Corradini, Giulio Cabrini, Roberto Gambari, Alessia Finotti

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Recent Cutting-Edge Technologies for the Delivery of Peptide Nucleic Acid.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Chiara PapiDepartment of Life Sciences and Biotechnology, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-9242-1766
Jessica GasparelloDepartment of Life Sciences and Biotechnology, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-8557-0739
Matteo ZurloDepartment of Life Sciences and Biotechnology, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-6131-3727
Alex ManicardiDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, Italy.ORCID 0000-0003-0083-1392
Roberto CorradiniDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, Italy.ORCID 0000-0002-8026-0923
Giulio CabriniDepartment of Life Sciences and Biotechnology, University of Ferrara, 44121 Ferrara, Italy.
Roberto GambariDepartment of Life Sciences and Biotechnology, University of Ferrara, 44121 Ferrara, Italy.
Alessia FinottiDepartment of Life Sciences and Biotechnology, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-7638-515X
University of Ferrara · ITUniversity of Parma · IT

Funding

Fondazione per la Ricerca sulla Fibrosi Cistica FFC#7/2016
6 · The paper itself

Abstract

The Cystic Fibrosis Transmembrane Conductance Regulator (

Indexed as

AntagomirsCystic FibrosisMicroRNAsPeptide Nucleic Acids3' Untranslated RegionsCystic Fibrosis Transmembrane Conductance RegulatorEpithelial CellsHumans3' Untranslated RegionsAntagomirsCFTR protein, humanCystic Fibrosis Transmembrane Conductance RegulatorMicroRNAsMIRN101 microRNA, humanMIRN145 microRNA, humanPeptide Nucleic AcidsCFTRcystic fibrosismicroRNAsmiR-101-3pmiR-145-5pmiRNA targetingpeptide nucleic acids

Identifiers

PMID36012615
PMCPMC9409490
OpenAlexW4293514566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.