Evidence map›Paper›PMID 36012545›Full record

ArticleInternational journal of molecular sciences2022

Dynamic Alteration Profile and New Role of RNA m6A Methylation in Replicative and H

Fan Wu, Luyun Zhang, Caiyun Lai, Xinyue Peng, Susu Yu, Cheng Zhou, Bo Zhang, Wenjuan Zhang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  10. Review
  11. Article
  12. NAging and disease · 2024
    Review
  13. Article
  14. Article
  15. Key mBMC medical genomics · 2023
    Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Fan WuFood Safety and Health Research Center, School of Public Health, Southern Medical University, Guangzhou 510515, China.
Luyun ZhangDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China.
Caiyun LaiDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China.
Xinyue PengDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China.
Susu YuDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China.
Cheng ZhouDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China.
Bo ZhangFood Safety and Health Research Center, School of Public Health, Southern Medical University, Guangzhou 510515, China.
Wenjuan ZhangDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China.ORCID 0000-0003-2922-0640
Jinan University · CNSouthern Medical University · CN

Funding

National Natural Science Foundation of China 81473014Natural Science Foundation of Guangdong Province of China 2021A1515011220Open Fund of State Key Laboratory of Respiratory Diseases of China SKLRD-OP-201810
6 · The paper itself

Abstract

N6-methyladenosine (m6A) methylation is one of the most common RNA modifications, regulating RNA fate at the posttranscriptional level, and is closely related to cellular senescence. Both models of replicative and premature senescence induced by hydrogen peroxide (H

Indexed as

FibroblastsHydrogen PeroxideAlpha-Ketoglutarate-Dependent Dioxygenase FTOHumansLungMethylationMethyltransferasesReactive Oxygen SpeciesRNAAlpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, humanHydrogen PeroxideMethyltransferasesMETTL16 protein, humanMETTL3 protein, humanReactive Oxygen SpeciesRNAm6Aoxidative stresspremature senescenceRNA methylation

Identifiers

PMID36012545
PMCPMC9408987
OpenAlexW4292163604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.