Evidence map›Paper›PMID 36012519›Full record

ArticleInternational journal of molecular sciences2022

Molecular Events behind the Selectivity and Inactivation Properties of Model NaK-Derived Ion Channels.

Ana Marcela Giudici, María Lourdes Renart, Ana Coutinho, Andrés Morales, José Manuel González-Ros, José Antonio Poveda

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ana Marcela GiudiciInstituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE), and Instituto de Biología Molecular y Celular (IBMC), Universidad Miguel Hernández, 03202 Elche, Spain.
María Lourdes RenartInstituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE), and Instituto de Biología Molecular y Celular (IBMC), Universidad Miguel Hernández, 03202 Elche, Spain.ORCID 0000-0002-6717-4756
Ana CoutinhoiBB-Institute for Bioengineering and Bioscience, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.ORCID 0000-0003-1653-0703
Andrés MoralesDepartamento de Fisiología, Genética y Microbiología, Universidad de Alicante, 03080 Alicante, Spain.
José Manuel González-RosInstituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE), and Instituto de Biología Molecular y Celular (IBMC), Universidad Miguel Hernández, 03202 Elche, Spain.
José Antonio PovedaInstituto de Investigación, Desarrollo e Innovación en Biotecnología Sanitaria de Elche (IDiBE), and Instituto de Biología Molecular y Celular (IBMC), Universidad Miguel Hernández, 03202 Elche, Spain.ORCID 0000-0003-0722-3752
Universitat de Miguel Hernández d'Elx · ESUniversity of Alicante · ESUniversity of Lisbon · PT

Funding

Associate Laboratory Institute for Health and Bioeconomy-i4HB LA/P/0140/2020Fundação para a Ciência e Tecnologia UIDB/04565/2020Ministerio de Ciencia e Innovación PGC2018-093505-B-I00
6 · The paper itself

Abstract

Y55W mutants of non-selective NaK and partly K

Indexed as

PotassiumPotassium ChannelsBacterial ProteinsBinding SitesIon ChannelsIonsProtein ConformationSodiumBacterial ProteinsIon ChannelsIonsPotassiumPotassium ChannelsSodiumanisotropy decaysconformational flexibilityhomo-FRETinactivationion bindingpotassium channelsselectivitythermal stabilitytime-resolved and steady-state anisotropy

Identifiers

PMID36012519
PMCPMC9409022
OpenAlexW4292163677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.