Evidence map›Paper›PMID 36012509›Full record

ArticleInternational journal of molecular sciences2022

The Modification of Offspring Stress-Related Behavior and the Expression of

Nikki Clauss, Kelsey Brass Allen, Katie D Billings, Mikayla D M Tolliver, Ray Garza, Jennifer Byrd-Craven, Polly Campbell

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 1 country.

Nikki ClaussDepartment of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr., San Antonio, TX 78229, USA.ORCID 0000-0003-1503-3836
Kelsey Brass AllenCollege of Medicine, University of Oklahoma Health Science Center, 1100 N Lindsay Ave, Oklahoma City, OK 73104, USA.
Katie D BillingsDepartment of Science and Mathematics, Mississippi College, Box 4053, Clinton, MS 39058, USA.
Mikayla D M TolliverDepartment of Psychological Science, 216 Memorial Hall, University of Arkansas, Fayetteville, AR 72701, USA.
Ray GarzaDepartment of Psychology and Communication, Texas A&M International University, 5201 University Blvd, Laredo, TX 78041, USA.ORCID 0000-0003-4307-2680
Jennifer Byrd-CravenDepartment of Psychology, Oklahoma State University, 116 Psychology Building, Stillwater, OK 74078, USA.ORCID 0000-0002-5854-7207
Polly CampbellDepartment of Evolution, Ecology, and Organismal Biology, University of California, Riverside, 900 University Ave, Riverside, CA 92521, USA.
Mississippi College · USOklahoma State University · USTexas A&M International University · USThe University of Texas Health Science Center at San Antonio · USUniversity of Arkansas at Fayetteville · USUniversity of California, Riverside · USUniversity of Oklahoma Health Sciences Center · US

Funding

National Sleep Foundation NSF-IOS714 1558109Sigma Xi NA
6 · The paper itself

Abstract

The impact of early developmental experience on neurobiological pathways that may contribute to the association between diet and behavior have not yet been elucidated. The focus of the current study was to determine whether the impact of prenatal stress (PS) could be mitigated by a diet that stimulates the same neuroendocrine systems influenced by early stress, using a mouse model. Behavioral and genetic approaches were used to assess how a Western-pattern diet (WPD) interacts with PS and sex to impact the expression of anxiety-like behavior in an open-field arena, as well as the expression of the glucocorticoid receptor in the hippocampus, D1 dopamine receptors in the nucleus accumbens, and D2 dopamine receptors in the ventral tegmental area. Overall, the results demonstrated that a prenatal WPD mitigates the effects of maternal stress in dams and offspring. These results help to elucidate the relationship between pre- and post-natal nutrition, gene expression, and behaviors that lead to long-term health effects.

Indexed as

Diet, WesternPrenatal Exposure Delayed EffectsReceptors, Dopamine D1Receptors, Dopamine D2Receptors, GlucocorticoidAnimalsFemaleHippocampusMiceNucleus AccumbensPregnancyStress, PsychologicalVentral Tegmental AreaDrd1 protein, mouseDRD2 protein, mouseNR3C1 protein, mouseReceptors, Dopamine D1Receptors, Dopamine D2Receptors, Glucocorticoiddevelopmentdietgene expressionmaternal behaviorsex differencesstress

Identifiers

PMID36012509
PMCPMC9409213
OpenAlexW4292164110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.