Evidence map›Paper›PMID 36012473›Full record

ReviewInternational journal of molecular sciences2022

Electrospun Biomimetic Nanofibrous Scaffolds: A Promising Prospect for Bone Tissue Engineering and Regenerative Medicine.

Shabnam Anjum, Farheen Rahman, Prashant Pandey, Dilip Kumar Arya, Mahmood Alam, Paruvathanahalli Siddalingam Rajinikanth, Qiang Ao

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 135 citations in OpenAlex.

  1. Multifunctional TPU-HAp/HA-TiOInternational journal of pharmaceutics: X · 2026
    Article
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  4. Nano-Based 3D Printed Scaffold for Bone Tissue Engineering.Bioengineering (Basel, Switzerland) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Shabnam AnjumDepartment of Tissue Engineering, School of Intelligent Medicine, China Medical University, Shenyang 110122, China.
Farheen RahmanDepartment of Applied Chemistry, Zakir Husain College of Engineering & Technology, Aligarh Muslim University, Aligarh 202002, India.
Prashant PandeyDepartment of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Raebareli Road, Lucknow 226025, India.ORCID 0000-0003-0700-914X
Dilip Kumar AryaDepartment of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Raebareli Road, Lucknow 226025, India.
Mahmood AlamDepartment of Clinical Medicine, China Medical University, Shenyang 110122, China.
Paruvathanahalli Siddalingam RajinikanthDepartment of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Raebareli Road, Lucknow 226025, India.ORCID 0000-0002-1000-4211
Qiang AoDepartment of Tissue Engineering, School of Intelligent Medicine, China Medical University, Shenyang 110122, China.ORCID 0000-0002-1309-1971
Babasaheb Bhimrao Ambedkar University · INChina Medical University · CNAligarh Muslim University · INSichuan University · CN

Funding

National Key R&D Program of China, and Sichuan Science and Technology Program (No. 2020YFF0426289), and (No. 2020YFH0008)
6 · The paper itself

Abstract

Skeletal-related disorders such as arthritis, bone cancer, osteosarcoma, and osteoarthritis are among the most common reasons for mortality in humans at present. Nanostructured scaffolds have been discovered to be more efficient for bone regeneration than macro/micro-sized scaffolds because they sufficiently permit cell adhesion, proliferation, and chemical transformation. Nanofibrous scaffolds mimicking artificial extracellular matrices provide a natural environment for tissue regeneration owing to their large surface area, high porosity, and appreciable drug loading capacity. Here, we review recent progress and possible future prospective electrospun nanofibrous scaffolds for bone tissue engineering. Electrospun nanofibrous scaffolds have demonstrated promising potential in bone tissue regeneration using a variety of nanomaterials. This review focused on the crucial role of electrospun nanofibrous scaffolds in biological applications, including drug/growth factor delivery to bone tissue regeneration. Natural and synthetic polymeric nanofibrous scaffolds are extensively inspected to regenerate bone tissue. We focused mainly on the significant impact of nanofibrous composite scaffolds on cell adhesion and function, and different composites of organic/inorganic nanoparticles with nanofiber scaffolds. This analysis provides an overview of nanofibrous scaffold-based bone regeneration strategies; however, the same concepts can be applied to other organ and tissue regeneration tactics.

Indexed as

NanofibersTissue EngineeringBiomimeticsBone and BonesHumansRegenerative MedicineTissue Scaffoldsbone defectsbone tissue regenerationelectrospinninggrowth factornanofiber compositenanofibrous scaffolds

Identifiers

PMID36012473
PMCPMC9408902
OpenAlexW4292295141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.