Evidence map›Paper›PMID 36012452›Full record

ArticleInternational journal of molecular sciences2022

DNA Methylation Profiles of

Georgina Pearson, Chenchen Song, Sonja Hohmann, Tatyana Prokhorova, Tanja Maria Sheldrick-Michel, Thomas Knöpfel

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  7. [Advances in research on gender differences in autism spectrum disorders].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Georgina PearsonLaboratory for Neuronal Circuit Dynamics, Imperial College London, London W12 0NN, UK.ORCID 0000-0002-3153-3059
Chenchen SongLaboratory for Neuronal Circuit Dynamics, Imperial College London, London W12 0NN, UK.ORCID 0000-0003-4574-6431
Sonja HohmannDepartment of Psychiatry, Department of Clinical Research, University of Southern Denmark, 5230 Odense, Denmark.
Tatyana ProkhorovaDepartment of Psychiatry, Department of Clinical Research, University of Southern Denmark, 5230 Odense, Denmark.
Tanja Maria Sheldrick-MichelDepartment of Psychiatry, Department of Clinical Research, University of Southern Denmark, 5230 Odense, Denmark.
Thomas KnöpfelLaboratory for Neuronal Circuit Dynamics, Imperial College London, London W12 0NN, UK.ORCID 0000-0002-5718-0765
Imperial College London · GBUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA methylation profiling has become a promising approach towards identifying biomarkers of neuropsychiatric disorders including autism spectrum disorder (ASD). Epigenetic markers capture genetic risk factors and diverse exogenous and endogenous factors, including environmental risk factors and complex disease pathologies. We analysed the differential methylation profile of a regulatory region of the

Indexed as

Autism Spectrum DisorderAutistic DisorderAdultDNA MethylationEpigenesis, GeneticHumansOrganoidsautismCTCFDNA methylationepigeneticsGABAGAD1organoids

Identifiers

PMID36012452
PMCPMC9408997
OpenAlexW4292295259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.