Evidence map›Paper›PMID 36012435›Full record

ArticleInternational journal of molecular sciences2022

Genotypes and Variants of BKPyV in Organ Donors after Brain Death.

Jacek Furmaga, Marek Kowalczyk, Olga Furmaga-Rokou, Christos A Rokos, Tomasz Zapolski, Leszek Krakowski, Andrzej Jakubczak, Sławomir Rudzki

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Jacek FurmagaDepartment of General and Transplant Surgery and Nutritional Treatment, Medical University of Lublin, 20-954 Lublin, Poland.
Marek KowalczykInstitute of Quality Assessment and Processing of Animal Products, University of Life Sciences in Lublin, 20-950 Lublin, Poland.ORCID 0000-0003-0631-4468
Olga Furmaga-RokouDepartment of Radiology, General Hospital of Thessaloniki George Papanicolaou, 56403 Thessaloniki, Greece.ORCID 0000-0001-5139-2890
Christos A RokosDepartment of Otolaryngology, Head and Neck Surgery, AHEPA University Hospital, Aristotle University of Thessaloniki, Kiriakidi 1, 54636 Thessaloniki, Greece.ORCID 0000-0001-5627-4201
Tomasz ZapolskiDepartment of Cardiology, Medical University of Lublin, 20-954 Lublin, Poland.ORCID 0000-0001-9808-8853
Leszek KrakowskiDepartment and Clinic of Animal Reproduction, Faculty of Veterinary Medicine, University of Life Sciences, Gleboka 30, 20-612 Lublin, Poland.ORCID 0000-0001-8868-5670
Andrzej JakubczakInstitute of Biological Basis of Animal Production, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, 20-950 Lublin, Poland.ORCID 0000-0001-8320-8349
Sławomir RudzkiDepartment of General and Transplant Surgery and Nutritional Treatment, Medical University of Lublin, 20-954 Lublin, Poland.
Medical University of Lublin · PLUniversity of Life Sciences in Lublin · PLAristotle University of Thessaloniki · GRG. Papanikolaou General Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kidney transplantation from a donor with latent BKPyV might be the cause of serious complications, such as BK virus-associated nephropathy. The aim of the study was to determine the prevalence of BKPyV infection in donors after brain death (DBDs), to analyse the molecular variation of BKPyV and to compare clinical and inflammation parameters of DBDs infected with various genotypes of BKPyV. BKPyV was investigated in blood and urine samples of 103 DBDs using PCR followed by sequencing and bioinformatic analysis, and the viral load was assessed by qPCR. Clinical parameters, including cellular markers of inflammation were assessed. The results confirm high prevalence of BKPyV (48%),and genotype IV (49%) over genotype I (43%) and the co-infection with genotypes I and IV in 8.2%. Viral load ranged from 10

Indexed as

BK VirusKidney DiseasesPolyomavirus InfectionsBrain DeathGenotypeHumansInflammationTissue DonorsTransplant RecipientsBKPyVcellular markers of inflammationco-infectiongenotypingkidney transplantationNLRviral load

Identifiers

PMID36012435
PMCPMC9409029
OpenAlexW4292070757

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.