Evidence map›Paper›PMID 36012402›Full record

ReviewInternational journal of molecular sciences2022

Nutrition as Personalized Medicine against SARS-CoV-2 Infections: Clinical and Oncological Options with a Specific Female Groups Overview.

Miriam Dellino, Eliano Cascardi, Marina Vinciguerra, Bruno Lamanna, Antonio Malvasi, Salvatore Scacco, Silvia Acquaviva, Vincenzo Pinto, Giovanni Di Vagno, Gennaro Cormio and 8 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. The "Magnificent Seven" in Oral and Systemic Health against COVID-19.Endocrine, metabolic & immune disorders drug targets · 2025
    Review
  4. Article
  5. Intrapartum ultrasound and mother acceptance: A study with informed consent and questionnaire.European journal of obstetrics & gynecology and reproductive biology: X · 2023
    Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 2 countries.

Miriam DellinoDepartment of Biomedical Sciences and Human Oncology, University of Bari, 70100 Bari, Italy.ORCID 0000-0003-3522-4648
Eliano CascardiDepartment of Medical Sciences, University of Turin, 10124 Turin, Italy.ORCID 0000-0003-1287-4285
Marina VinciguerraDepartment of Biomedical Sciences and Human Oncology, University of Bari, 70100 Bari, Italy.ORCID 0000-0003-4771-6287
Bruno LamannaDepartment of Biomedical Sciences and Human Oncology, University of Bari, 70100 Bari, Italy.
Antonio MalvasiDepartment of Biomedical Sciences and Human Oncology, University of Bari, 70100 Bari, Italy.
Salvatore ScaccoDepartment of Basic Medical Sciences and Neurosciences, University of Bari "Aldo Moro", 70121 Bari, Italy.ORCID 0000-0003-2717-2489
Silvia AcquavivaDepartment of Basic Medical Sciences and Neurosciences, University of Bari "Aldo Moro", 70121 Bari, Italy.
Vincenzo PintoDepartment of Biomedical Sciences and Human Oncology, University of Bari, 70100 Bari, Italy.
Giovanni Di VagnoClinic of Obstetrics and Gynecology, "San Paolo" Hospital, 70123 Bari, Italy.
Gennaro CormioGynecologic Oncology Unit, IRCCS Istituto Tumori Giovanni Paolo II, Department of Interdisciplinary Medicine (DIM), University of Bari "Aldo Moro", 70121 Bari, Italy.ORCID 0000-0001-5745-372X
Raffaele De LucaIRCCS Istituto Tumori Giovanni Paolo II, 70124 Bari, Italy.ORCID 0000-0002-9337-0769
Miria LafranceschinaIRCCS Istituto Tumori Giovanni Paolo II, 70124 Bari, Italy.
Gerardo CazzatoDepartment of Emergency and Organ Transplantation, University of Bari "Aldo Moro", 70121 Bari, Italy.ORCID 0000-0003-0325-4316
Giuseppe IngravalloDepartment of Emergency and Organ Transplantation, University of Bari "Aldo Moro", 70121 Bari, Italy.ORCID 0000-0002-4792-3545
Eugenio MaioranoDepartment of Emergency and Organ Transplantation, University of Bari "Aldo Moro", 70121 Bari, Italy.ORCID 0000-0002-0472-5338
Leonardo RestaDepartment of Emergency and Organ Transplantation, University of Bari "Aldo Moro", 70121 Bari, Italy.ORCID 0000-0003-4335-4776
Antonella DanieleIRCCS Istituto Tumori Giovanni Paolo II, 70124 Bari, Italy.ORCID 0000-0002-1323-9497
Daniele La ForgiaIRCCS Istituto Tumori Giovanni Paolo II, 70124 Bari, Italy.ORCID 0000-0002-3902-4523
University of Bari Aldo Moro · ITIstituto Tumori Bari · ITOspedale San Paolo · ITCandiolo Cancer Institute · ITKing's College Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) is a respiratory disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). It is acknowledged that vulnerable people can suffer from mortal complications of COVID-19. Therefore, strengthening the immune system particularly in the most fragile people could help to protect them from infection. First, general nutritional status and food consumption patterns of everyone affect the effectiveness of each immune system. The effects of nutrition could impact the level of intestinal and genital microbiota, the adaptive immune system, and the innate immune system. Indeed, immune system cells and mediators, which are crucial to inflammatory reaction, are in the structures of fats, carbohydrates, and proteins and are activated through vitamins (vit) and minerals. Therefore, the association of malnutrition and infection could damage the immune response, reducing the immune cells and amplifying inflammatory mediators. Both amount and type of dietary fat impact on cytokine biology, that consequently assumes a crucial role in inflammatory disease. This review explores the power of nutrition in the immune response against COVID-19 infection, since a specific diet could modify the cytokine storm during the infection phase. This can be of vital importance in the most vulnerable subjects such as pregnant women or cancer patients to whom we have deemed it necessary to dedicate personalized indications.

Indexed as

COVID-19Cytokine Release SyndromeFemaleHumansNutritional StatusPrecision MedicinePregnancySARS-CoV-2cancercarcinomaCOVID-19health promotionketogenic dietmetabolomicsmicrobiotanutrition in pregnancyprecision medicineSARS-CoV-2

Identifiers

PMID36012402
PMCPMC9409275
OpenAlexW4292068853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.