Evidence map›Paper›PMID 36012339›Full record

ReviewInternational journal of molecular sciences2022

Human RNASET2: A Highly Pleiotropic and Evolutionary Conserved Tumor Suppressor Gene Involved in the Control of Ovarian Cancer Pathogenesis.

Antonino Bruno, Douglas M Noonan, Roberto Valli, Giovanni Porta, Roberto Taramelli, Lorenzo Mortara, Francesco Acquati

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Pathogenic Roles for RNASET2 in Clear Cell Renal Cell Carcinoma.Laboratory investigation; a journal of technical methods and pathology · 2024
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Antonino BrunoImmunology and General Pathology Laboratory, Department of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.ORCID 0000-0002-4790-0861
Douglas M NoonanImmunology and General Pathology Laboratory, Department of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.ORCID 0000-0001-8058-0719
Roberto ValliDepartment of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.ORCID 0000-0002-3209-8917
Giovanni PortaDepartment of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.
Roberto TaramelliHuman Genetics Laboratory, Department of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.
Lorenzo MortaraImmunology and General Pathology Laboratory, Department of Biotechnology and Life Sciences, University of Insubria, 21100 Varese, Italy.ORCID 0000-0002-4757-7101
Francesco AcquatiGenomic Medicine Research Center, Department of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.ORCID 0000-0002-9537-400X
University of Insubria · IT

Funding

FAR-2020 and FAR 2021 2020-2021Fondazione Cariplo 2019-1609Italian Association for Cancer Research 22818Ministry of Education, Universities and Research 2017NTK4HY
6 · The paper itself

Abstract

Ovarian cancer represents one of the most malignant gynecological cancers worldwide, with an overall 5-year survival rate, being locked in the 25-30% range in the last decade. Cancer immunotherapy is currently one of the most intensively investigated and promising therapeutic strategy and as such, is expected to provide in the incoming years significant benefits for ovarian cancer treatment as well. Here, we provide a detailed survey on the highly pleiotropic oncosuppressive roles played by the human

Indexed as

Ovarian NeoplasmsRibonucleasesTumor Suppressor ProteinsFemaleGenes, Tumor SuppressorHumansRibonucleasesRNASET2 protein, humanTumor Suppressor Proteinsovarian cancerRNASET2tumor microenvironmenttumor suppressor genes

Identifiers

PMID36012339
PMCPMC9409134
OpenAlexW4291465490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.