Evidence map›Paper›PMID 36012303›Full record

ArticleInternational journal of molecular sciences2022

ADAR1 Isoforms Regulate

Gabriela Díaz-Piña, Karla Rubio, Rosa M Ordoñez-Razo, Guillermo Barreto, Eduardo Montes, Carina Becerril, Alfonso Salgado, Héctor Cabrera-Fuentes, Arnoldo Aquino-Galvez, Angeles Carlos-Reyes and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Targeting RNA adenosine editing and modification enzymes for RNA therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  3. Article
  4. Review
  5. The role of ADAR1 in human pathophysiology.Frontiers in cell and developmental biology · 2025
    Review
  6. Review
  7. RNA binding proteins in cardiovascular development and disease.Current topics in developmental biology · 2024
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Gabriela Díaz-PiñaMolecular Biology Laboratory, Pulmonary Fibrosis Department, National Institute of Respiratory Diseases "Ismael Cosío Villegas", Calzada de Tlalpan No. 4502, Col. Sección XVI, Mexico City 14080, Mexico.ORCID 0000-0002-9732-5965
Karla RubioUniversité de Lorraine, CNRS, Laboratoire IMoPA, UMR 7365, F-54000 Nancy, France.ORCID 0000-0002-8337-3106
Rosa M Ordoñez-RazoMedical Research Unit in Human Genetics, Pediatric Hospital "Dr. Silvestre Frenk Freud", National Medical Center "Siglo XXI", Mexican Social Security Institute, Av. Cuauhtémoc No. 330, Col. Doctores, Delegación Cuauhtémoc, Mexico City 06720, Mexico.ORCID 0000-0003-4949-9175
Guillermo BarretoUniversité de Lorraine, CNRS, Laboratoire IMoPA, UMR 7365, F-54000 Nancy, France.ORCID 0000-0002-7777-4712
Eduardo MontesMolecular Biology Laboratory, Pulmonary Fibrosis Department, National Institute of Respiratory Diseases "Ismael Cosío Villegas", Calzada de Tlalpan No. 4502, Col. Sección XVI, Mexico City 14080, Mexico.
Carina BecerrilCellular Biology Laboratory, Pulmonary Fibrosis Department, National Institute of Respiratory Diseases "Ismael Cosío Villegas", Calzada de Tlalpan No. 4502, Col. Sección XVI, Mexico City 14080, Mexico.
Alfonso SalgadoRheumatic Diseases Research Laboratory, Pulmonary Fibrosis Department, National Institute of Respiratory Diseases "Ismael Cosío Villegas", Calzada de Tlalpan No. 4502, Col. Sección XVI, Mexico City 14080, Mexico.ORCID 0000-0001-8102-3690
Héctor Cabrera-FuentesMedical School, Institute of Biochemistry, Justus-Liebig-University, 35390 Giessen, Germany.
Arnoldo Aquino-GalvezMolecular Biology Laboratory, Pulmonary Fibrosis Department, National Institute of Respiratory Diseases "Ismael Cosío Villegas", Calzada de Tlalpan No. 4502, Col. Sección XVI, Mexico City 14080, Mexico.ORCID 0000-0002-2869-5516
Angeles Carlos-ReyesOnco-Immunobiology Laboratory, Department of Chronic-Degenerative Diseases, National Institute of Respiratory Diseases "Ismael Cosío Villegas", Calzada de Tlalpan No. 4502, Col. Sección XVI, Mexico City 14080, Mexico.
Victor RuizMolecular Biology Laboratory, Pulmonary Fibrosis Department, National Institute of Respiratory Diseases "Ismael Cosío Villegas", Calzada de Tlalpan No. 4502, Col. Sección XVI, Mexico City 14080, Mexico.ORCID 0000-0003-0440-2093
Centre National de la Recherche Scientifique · FRJustus-Liebig-Universität Gießen · DEMexican Social Security Institute · MX

Funding

Centre National de la Recherche Scientifique "Lorraine Université d'Excellence" (LUE) and the dispositive "Future Leader"CONCYTEP, Puebla, México International Laboratory EPIGEN"Deutsche Forschungsgemeinschaft" BA 4036/4-1Instituto Nacional de Enfermedades Respiratorias Research budget
6 · The paper itself

Abstract

Double-stranded RNA adenosine deaminase 1 (ADAR1) is significantly down-regulated in fibroblasts derived from Idiopathic Pulmonary Fibrosis (IPF) patients, and its overexpression restored levels of

Indexed as

Adenosine DeaminaseIdiopathic Pulmonary FibrosisMicroRNAsHumansIntracellular Signaling Peptides and ProteinsLungMembrane ProteinsProtein IsoformsRNA-Binding ProteinsADAR protein, humanAdenosine DeaminaseIntracellular Signaling Peptides and ProteinsMembrane ProteinsMicroRNAsmirnlet7 microRNA, humanProtein IsoformsRNA-Binding ProteinsSPRY2 protein, humanADARIPFmiRNARNA edition

Identifiers

PMID36012303
PMCPMC9409484
OpenAlexW4291777198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.