Evidence map›Paper›PMID 36012298›Full record

ArticleInternational journal of molecular sciences2022

SIRT7 Deficiency Protects against Aβ

Hironori Mizutani, Yoshifumi Sato, Masaya Yamazaki, Tatsuya Yoshizawa, Yukio Ando, Mitsuharu Ueda, Kazuya Yamagata

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Frontiers in cellular and infection microbiology · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hironori MizutaniDepartment of Medical Biochemistry, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0000-0002-2013-7368
Yoshifumi SatoDepartment of Medical Biochemistry, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0000-0003-0697-1476
Masaya YamazakiDepartment of Medical Biochemistry, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0000-0003-4151-4983
Tatsuya YoshizawaDepartment of Medical Biochemistry, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.ORCID 0000-0002-5728-1996
Yukio AndoDepartment of Amyloidosis Research, Faculty of Pharmaceutical Sciences, Nagasaki International University, 2825-7 Huis Ten Bosch Sasebo, Nagasaki 859-3298, Japan.
Mitsuharu UedaDepartment of Neurology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-0811, Japan.
Kazuya YamagataDepartment of Medical Biochemistry, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.
Kumamoto University · JPNagasaki International University · JP

Funding

a grant from the Japan Agency for Medical Research and Development under Grant Number JP21gm5010002a Grant-in-Aid for Challenging Research 19K22639a Grant-in-Aid for Scientific Research (B) 19H03711a Grant-in-Aid for Scientific Research (B) 22H03129a Grant-in-Aid for Scientific Research (C) 19K09008
6 · The paper itself

Abstract

Alzheimer's disease (AD) is an age-related neurodegenerative disease that is characterized by irreversible memory loss and cognitive decline. The deposition of amyloid-β (Aβ), especially aggregation-prone Aβ

Indexed as

Alzheimer DiseaseNeuroblastomaNeurodegenerative DiseasesSirtuinsAmyloid beta-PeptidesApoptosisCell Line, TumorHumansNADPH Oxidase 4Peptide FragmentsReactive Oxygen SpeciesAmyloid beta-PeptidesNADPH Oxidase 4NOX4 protein, humanPeptide FragmentsReactive Oxygen SpeciesSIRT7 protein, humanSirtuinsAlzheimer’s diseaseamyloid-βapoptosisNADPH oxidasereactive oxygen speciesSIRT7

Identifiers

PMID36012298
PMCPMC9408927
OpenAlexW4291465487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.