Evidence map›Paper›PMID 36012215›Full record

ArticleInternational journal of molecular sciences2022

Miao-Yi Wu, Chia-Chu Liu, Su-Chu Lee, Yueh-Hsiung Kuo, Tusty-Jiuan Hsieh

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Miao-Yi WuGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.ORCID 0000-0003-0713-0046
Chia-Chu LiuResearch Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
Su-Chu LeeDivision of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
Yueh-Hsiung KuoDepartment of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung 406040, Taiwan.ORCID 0000-0001-5935-6755
Tusty-Jiuan HsiehGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.ORCID 0000-0001-5387-6522
Kaohsiung Medical University · TWAsia University · TWNational Sun Yat-sen University · TW

Funding

Ministry of Science and Technology in Taiwan MOST 107-2314-B-037-016-MY2
6 · The paper itself

Abstract

The underlying pathological mechanisms of diabetes are complicated and varied in diabetic patients, which may lead to the current medications often failing to maintain glycemic control in the long term. Thus, the discovery of diverse new compounds for developing medicines to treat diabetes and its complications are urgently needed. Polyphenols are metabolites of plants and have been employed in the prevention and treatment of a variety of diseases. Caffeic acid phenethyl ester (CAPE) is a category of compounds structurally similar to polyphenols. In this study, we aimed to investigate the antidiabetic activity and potential molecular mechanisms of a novel synthetic CAPE derivative

Indexed as

Diabetes MellitusFatty LiverAmidesAMP-Activated Protein KinasesAnimalsCaffeic AcidsDiet, High-FatLiverMiceMice, Inbred C57BLMice, ObesePolyphenolsAmidesAMP-Activated Protein Kinasescaffeic acidCaffeic AcidsPolyphenolsAMPKFsp27lipid dropletobesityperilipinPTP1B

Identifiers

PMID36012215
PMCPMC9409300
OpenAlexW4290999001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.