Evidence map›Paper›PMID 36011603›Full record

ReviewInternational journal of environmental research and public health2022

Changes in the Gut Microbiome and Pathologies in Pregnancy.

Kamila Gorczyca, Aleksandra Obuchowska, Żaneta Kimber-Trojnar, Magdalena Wierzchowska-Opoka, Bożena Leszczyńska-Gorzelak

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 98 citations in OpenAlex.

  1. Imbalance of gut microbiota in gestational diabetes.BMC pregnancy and childbirth · 2024
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  17. Observational
  18. Computational Metagenomics: State of the Art.International journal of molecular sciences · 2025
    Review
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kamila GorczycaDepartment of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0002-7976-0509
Aleksandra ObuchowskaDepartment of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.
Żaneta Kimber-TrojnarDepartment of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0001-7295-0409
Magdalena Wierzchowska-OpokaDepartment of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.
Bożena Leszczyńska-GorzelakDepartment of Obstetrics and Perinatology, Medical University of Lublin, 20-090 Lublin, Poland.
Medical University of Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy is a special period in a woman's life when her organism undergoes multiple physiological changes so that the fetus has optimal conditions for growth and development. These include modifications in the composition of the microbiome that occur between the first and third trimesters of pregnancy. There is an increase in Akkermansia, Bifidobacterium, and Firmicutes, which have been associated with an increase in the need for energy storage. The growth in Proteobacteria and Actinobacteria levels has a protective effect on both the mother and the fetus via proinflammatory mechanisms. The aim of the study is to review the research on the relationship between the mother's intestinal microbiome and gestational pathologies. Changes in the maternal gut microbiome is probably one of the mechanisms that occurs in various pregnancy diseases such as preeclampsia, fetal growth restriction, gestational diabetes mellitus, excessive gestational weight gain, and premature birth. For this reason, it seems vital to pay attention to certain interventions that can benefit the affected patients both in the short term, by preventing complications during pregnancy, and in the long term, as one of the mechanisms occurring in various gestational diseases is dysbiosis of the maternal intestinal flora.

Indexed as

Gastrointestinal MicrobiomeGestational Weight GainPregnancy ComplicationsBifidobacteriumDysbiosisFemaleHumansPregnancyWeight Gaincervical insufficiencyfetal growth restrictiongestational diabetes mellitusgut microbiotamicrobiomeobesitypreeclampsiapregnancypremature birth

Identifiers

PMID36011603
PMCPMC9408136
OpenAlexW4291890880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.