Evidence map›Paper›PMID 36011226›Full record

ArticleHealthcare (Basel, Switzerland)2022

Neuroendocrine Tumors: An Analysis of Prevalence, Incidence, and Survival in a Hospital-Based Study in Ecuador.

Karime Montes Escobar, Jose Luis Vicente-Villardon, Rosa Elisa Villacís Gonzalez, Paul Humberto Castillo Cordova, Johanna Mabel Sánchez Rodríguez, Melina De la Cruz-Velez, Aline Siteneski

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Karime Montes EscobarDepartment of Mathematics and Statistics, Institute of Basic Sciences, Universidad Técnica de Manabí, Portoviejo 130105, Ecuador.ORCID 0000-0002-9555-0392
Jose Luis Vicente-VillardonStatistics Department, University of Salamanca, 37007 Salamanca, Spain.ORCID 0000-0003-1416-6813
Rosa Elisa Villacís GonzalezTeaching and Research, SOLCA, El Oro, Machala 070206, Ecuador.
Paul Humberto Castillo CordovaTeaching and Research, SOLCA, Loja 110150, Ecuador.
Johanna Mabel Sánchez RodríguezFacultad de Medicina, Universidad Laica Eloi Alfaro de Manabí, Manta 130203, Ecuador.
Melina De la Cruz-VelezFaculty of Health Sciences, Medicine Career, Universidad Técnica de Manabí, Portoviejo 130105, Ecuador.
Aline SiteneskiResearch Institute, Universidad Técnica de Manabí, Portoviejo 130105, Ecuador.ORCID 0000-0001-6692-7253
Universidad de Salamanca · ESUniversidad Técnica de Manabí · ECUniversidad Laica Eloy Alfaro de Manabí · ECUniversidad Nacional de Loja · EC

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroendocrine tumors (NETs) represent a heterogeneous malignancy group of neoplasms, with a limited amount of data from Latin America. Thus, this observational study aimed to provide data about the prevalence, incidence, and survival rates for NET in Ecuadorian hospitals. The study was conducted using data from the Society for the Fight Against Cancer (SOLCA). We evaluated patients with NETs (2000−2020) using the HJ-Biplot method and Cox proportional hazards. Annual age-adjusted incidence and limited-duration prevalence in multivariable analyses as well as hazard ratios (HRs) for mortality and survival were obtained. In the years 2000−2020, the age-adjusted incidence rate increased by 9-fold in the stomach and by 7-fold in the breast. The incidence rates were 1.38 per 100,000 persons in the lung and at 1.79 per 100,000 persons in gastroenteropancreatic sites (rectum, stomach, and pancreas). The prevalence increased from 0.0027% in 2000 to 0.0736% in 2019 and 0.0245% in 2020. Overall survival was worse for metastatic NETs (HR, 4.061; 95% CI, 1.932−8.540; p < 0.001) and advanced local NETs (HR, 2.348; 95% CI, 1.007−5.475 p < 0.048) than for localized NETs. In conclusion, the NET incidence increased in the last 20 years and survival decreased over time, especially for metastatic tumors in the pancreas and the nostril.

Indexed as

HJ-Biplotincidenceneuroendocrine tumorpopulationprevalencesurvival

Identifiers

PMID36011226
PMCPMC9408119
OpenAlexW4292247166

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.