Evidence map›Paper›PMID 36011029›Full record

ReviewCancers2022

Dendritic Cell Vaccines: A Promising Approach in the Fight against Ovarian Cancer.

Aarushi Audhut Caro, Sofie Deschoemaeker, Lize Allonsius, An Coosemans, Damya Laoui

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Fungal immunization potentiates CD4Frontiers in immunology · 2025
    Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Immunotherapeutic Approaches in Ovarian Cancer.Current issues in molecular biology · 2023
    Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Aarushi Audhut CaroLaboratory of Myeloid Cell Immunology, VIB Center for Inflammation Research, 1050 Brussels, Belgium.
Sofie DeschoemaekerLaboratory of Myeloid Cell Immunology, VIB Center for Inflammation Research, 1050 Brussels, Belgium.ORCID 0000-0001-5449-282X
Lize AllonsiusLaboratory of Myeloid Cell Immunology, VIB Center for Inflammation Research, 1050 Brussels, Belgium.ORCID 0000-0002-4133-5021
An CoosemansLaboratory of Tumor Immunology and Immunotherapy, Department of Oncology, Leuven Cancer Institute, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-7321-4339
Damya LaouiLaboratory of Myeloid Cell Immunology, VIB Center for Inflammation Research, 1050 Brussels, Belgium.ORCID 0000-0002-3373-1403
Vrije Universiteit Brussel · BEKU Leuven · BE

Funding

Research Foundation - Flanders 1169521NResearch Foundation - Flanders 12Z1820NResearch Foundation - Flanders G053321NStichting tegen Kanker 2021-023
6 · The paper itself

Abstract

Ovarian cancer (OC) is the deadliest gynecological malignancy in developed countries and is the seventh-highest cause of death in women diagnosed with cancer worldwide. Currently, several therapies are in use against OC, including debulking surgery, chemotherapy, as well as targeted therapies. Even though the current standard-of-care therapies improve survival, a vast majority of OC patients relapse. Additionally, immunotherapies have only resulted in meager patient outcomes, potentially owing to the intricate immunosuppressive nexus within the tumor microenvironment. In this scenario, dendritic cell (DC) vaccination could serve as a potential addition to the therapeutic options available against OC. In this review, we provide an overview of current therapies in OC, focusing on immunotherapies. Next, we highlight the potential of using DC vaccines in OC by underscoring the different DC subsets and their functions in OC. Finally, we provide an overview of the advances and pitfalls of current DC vaccine strategies in OC while providing future perspectives that could improve patient outcomes.

Indexed as

dendritic cell vaccinesimmunotherapyovarian cancerT cellstumor-antigens

Identifiers

PMID36011029
PMCPMC9406463
OpenAlexW4292546361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.