ReviewCancers2022
Early-Onset Cancers in Adults: A Review of Epidemiology, Supportive Care Needs and Future Research Priorities.
Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- "Management of andrological disorders from childhood and adolescence to transition age: guidelines from the Italian Society of Andrology and Sexual Medicine (SIAMS) in collaboration with the Italian Society for Pediatric Endocrinology and Diabetology (SIEDP)-Part-1".Journal of endocrinological investigation · 2025Guideline
- Can cognitive function tests discriminate between patients with glioma and healthy controls prior to treatment? A systematic review.PloS one · 2025Pooled it
- The Association between Early-Onset Pancreatic Ductal Adenocarcinoma and Patients Survival: A Systematic Review and Meta-Analysis.F1000Research · 2024Pooled it
- Are Social Media Platforms an Effective Forum for Engaging Early-Onset Cancer Survivors? Insights From X (Formerly Twitter).Asia-Pacific journal of clinical oncology · 2026Article
- Increasing Burden of Early-Onset Cancers: Disentangling the Contributions of Changes in Risk from Demographic Shifts.Cancer research communications · 2026Article
- Characteristics, Treatments, and Outcomes of Early-Onset Appendiceal Cancer: NCDB Analysis.Journal of gastrointestinal cancer · 2026Article
- Working through cancer: Economic precarity and the social meaning of survival for parent-survivors in the United States.Medical anthropology quarterly · 2026Article
- Clinical characteristics and outcomes in patients with early-onset locally advanced rectal cancer.Therapeutic advances in medical oncology · 2026Article
- Lipidomic signatures as predictive biomarkers for early-onset lung cancer: Identification and development of a risk prediction model.Journal of advanced research · 2026Article
- What cancers are increasing in young adults: a population-based study of incidence trends in adults 20-49 years old in the South of Spain.BMC public health · 2025Article
- Impact of oncology review meetings on second opinions for patients with gastrointestinal cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Trends in the disease burden of early-onset cancers in China from 1990 to 2021: a systematic analysis of the 2021 Global Burden of Disease study.BMC cancer · 2025Article
- Prioritizing the Timely Detection and Diagnosis of Early-Age Onset Cancer to Enable Optimal Disease Management and Outcomes.Current oncology (Toronto, Ont.) · 2025Article
- Tongue squamous cell carcinoma masked by herpes simplex virus infection: A case report.Oncology letters · 2025Article
- Demographic, Disease, and Treatment Characteristics of Primary Tracheal Cancers.Annals of surgical oncology · 2025Article
- Smoking cessation is a protective factor for lung cancer onset and mortality: a population-based prospective cohort study.BMC cancer · 2025Article
- Parenting and Family Concerns of Couples Navigating Advanced Breast Cancer: Exploring Discussions Around Parenting Challenges and Targets for Intervention.Psycho-oncology · 2025Article
- Early-onset and later-onset cancer: trends, risk factors, and prevention in Northern China.Science China. Life sciences · 2024Article
- Kidney Cancer Incidence among Non-Hispanic American Indian and Alaska Native Populations in the United States, 1999 to 2020.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Article
- Understanding Colorectal Cancer Patient Experiences with Family Practitioners in Canada.Current oncology (Toronto, Ont.) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Rising incidence of specific types of early-age onset cancers in adults aged 18-49 years has been reported in high-income countries. In this review, we summarise the epidemiology of early-onset cancers using exemplar data from a high-income UK region, discuss supportive care needs for young patients and outline future research directions. The incidence rate of early-onset cancers increased by 20.5% from 1993 to 2019 in Northern Ireland. Differences in types of cancer were observed between sexes and across age groups of 18-29, 30-39 and 40-49 years. One and five-year net survival was mostly better in 18-29-year-olds for all cancers combined compared to older age groups for both sexes, but there were variations in specific cancer types. Poorer survival was observed for patients with brain/central nervous system, connective and soft tissue or lung cancers. Patients with early-onset cancers face unique supportive care needs and require holistic care. The impact of cancer treatment on fertility and fertility preservation treatments is an important consideration. Social media can be used for patient support, information, fundraising, advocacy work and recruitment to research studies. We also outline suggested future research priorities for early-onset cancers, spanning prevention, diagnosis, treatment and supportive care needs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.