Evidence map›Paper›PMID 36010944›Full record

ArticleCancers2022

Multidisciplinary Tumor Board in the Management of Patients with Colorectal Liver Metastases: A Single-Center Review of 847 Patients.

Flavio Milana, Simone Famularo, Antonio Luberto, Lorenza Rimassa, Marta Scorsetti, Tiziana Comito, Tiziana Pressiani, Ciro Franzese, Dario Poretti, Luca Di Tommaso and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Flavio MilanaDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, MI, Italy.ORCID 0000-0003-3570-9573
Simone FamularoDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, MI, Italy.ORCID 0000-0002-9721-6304
Antonio LubertoDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, MI, Italy.ORCID 0000-0002-1202-9447
Lorenza RimassaDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, MI, Italy.ORCID 0000-0001-9957-3615
Marta ScorsettiRadiotherapy and Radiosurgery Department, IRCCS Humanitas Research Hospital, 20089 Rozzano, MI, Italy.
Tiziana ComitoRadiotherapy and Radiosurgery Department, IRCCS Humanitas Research Hospital, 20089 Rozzano, MI, Italy.
Tiziana PressianiHumanitas Cancer Center, IRCCS Humanitas Research Hospital, 20089 Rozzano, MI, Italy.
Ciro FranzeseDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, MI, Italy.
Dario PorettiDepartment of Radiology, IRCCS Humanitas Research Hospital, 20089 Rozzano, MI, Italy.
Luca Di TommasoDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, MI, Italy.ORCID 0000-0002-9013-4728
Nicola PersoneniDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, MI, Italy.ORCID 0000-0002-7995-272X
Marcello RodariDepartment of Nuclear Medicine, IRCCS Humanitas Research Hospital, 20089 Rozzano, MI, Italy.
Vittorio PediciniDepartment of Radiology, IRCCS Humanitas Research Hospital, 20089 Rozzano, MI, Italy.
Matteo DonadonDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, MI, Italy.ORCID 0000-0003-0296-7648
Guido TorzilliDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, MI, Italy.ORCID 0000-0001-5798-5021
Humanitas University · ITIRCCS Humanitas Research Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is still debate over how reviewing oncological histories and addressing appropriate therapies in multidisciplinary team (MDT) discussions may affect patients’ overall survival (OS). The aim of this study was to describe MDT outcomes for a single cancer center’s patients affected by colorectal liver metastases (CRLMs). From 2010 to 2020, a total of 847 patients with CRLMs were discussed at our weekly MDT meeting. Patients’ characteristics and MDT decisions were analyzed in two groups: patients receiving systemic therapy (ST) versus patients receiving locoregional treatment (LRT). Propensity-score matching (PSM) was run to reduce the risk of selection bias. The median time from MDT indication to treatment was 27 (IQR 13−51) days. The median OS was 30 (95%CI = 27−34) months. After PSM, OS for patients undergoing LRT was 51 (95%CI = 36−64) months compared with 15 (95%CI = 13−20) months for ST patients (p < 0.0001). In this large retrospective study, the MDT discussions were useful in providing the patients with all available locoregional options.

Indexed as

colorectal cancercolorectal liver metastasesmultidisciplinary team meeting

Identifiers

PMID36010944
PMCPMC9405848
OpenAlexW4292261743

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.