Evidence map›Paper›PMID 36010891›Full record

ReviewCancers2022

Challenges in Glioblastoma Radiomics and the Path to Clinical Implementation.

Philip Martin, Lois Holloway, Peter Metcalfe, Eng-Siew Koh, Caterina Brighi

Abstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Philip MartinCentre for Medical and Radiation Physics, School of Physics, University of Wollongong, Wollongong, NSW 2522, Australia.
Lois HollowayCentre for Medical and Radiation Physics, School of Physics, University of Wollongong, Wollongong, NSW 2522, Australia.
Peter MetcalfeCentre for Medical and Radiation Physics, School of Physics, University of Wollongong, Wollongong, NSW 2522, Australia.
Eng-Siew KohIngham Institute for Applied Medical Research, Liverpool, NSW 2170, Australia.
Caterina BrighiIngham Institute for Applied Medical Research, Liverpool, NSW 2170, Australia.ORCID 0000-0001-9407-5772

Funding

National Health and Medical Research Council APP1132471South West Sydney Radiation Oncology PhD Top Up Scholarship
6 · The paper itself

Abstract

Radiomics is a field of medical imaging analysis that focuses on the extraction of many quantitative imaging features related to shape, intensity and texture. These features are incorporated into models designed to predict important clinical or biological endpoints for patients. Attention for radiomics research has recently grown dramatically due to the increased use of imaging and the availability of large, publicly available imaging datasets. Glioblastoma multiforme (GBM) patients stand to benefit from this emerging research field as radiomics has the potential to assess the biological heterogeneity of the tumour, which contributes significantly to the inefficacy of current standard of care therapy. Radiomics models still require further development before they are implemented clinically in GBM patient management. Challenges relating to the standardisation of the radiomics process and the validation of radiomic models impede the progress of research towards clinical implementation. In this manuscript, we review the current state of radiomics in GBM, and we highlight the barriers to clinical implementation and discuss future validation studies needed to advance radiomics models towards clinical application.

Indexed as

biomarkerGlioblastomamachine learningMRIradiomics

Identifiers

PMID36010891
PMCPMC9406186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.