Evidence map›Paper›PMID 36010881›Full record

ArticleCancers2022

Associations of Body Mass Index and Waist Circumference with the Risk of Head and Neck Cancer: A National Population-Based Study.

Choung-Soo Kim, Jun-Ook Park, Inn-Chul Nam, Sung Joon Park, Dong-Hyun Lee, Hyun-Bum Kim, Kyung-Do Han, Young-Hoon Joo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  4. A multimodal approach for establishingFrontiers in pharmacology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Choung-Soo KimDepartment of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul 07345, Korea.ORCID 0000-0002-9551-9571
Jun-Ook ParkDepartment of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul 07345, Korea.ORCID 0000-0001-7118-3463
Inn-Chul NamDepartment of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul 07345, Korea.
Sung Joon ParkDepartment of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University College of Medicine, Chung-Ang University Gwangmyeong Hospital, Gwangmyeon-si 14353, Korea.ORCID 0000-0001-6370-5997
Dong-Hyun LeeDepartment of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul 07345, Korea.ORCID 0000-0003-4049-2823
Hyun-Bum KimDepartment of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul 07345, Korea.ORCID 0000-0003-1802-8952
Kyung-Do HanDepartment of Statistics and Actuarial Science, Soongsil University, Seoul 06978, Korea.
Young-Hoon JooDepartment of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul 07345, Korea.ORCID 0000-0002-1158-0974
Catholic University of Korea · KRChung-Ang University · KRSoongsil University · KR

Funding

Korea Medical Device Development Fund grant 202011D15
6 · The paper itself

Abstract

Background: We investigated the association between BMI and HNC subtype incidence in a cohort study of ten million people, adjusting for the effect of smoking and drinking. We also investigated the relationship between waist circumference (WC) and HNC subtype. Methods: All data used in this study originated from the Korean National Health Insurance Service database. We analysed subjects who had undergone health check-ups in 2009 and monitored subjects until 2018 (n = 10,585,852). Finally, 9,598,085 subjects were included after exclusions. We collected variables that could affect the risk of HNC. Cox proportional hazards regression analysis was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). Results: The overall incidence of HNC was higher in the low BMI category (BMI < 18.5 according to WHO recommendations for Asian people) (HR: 1.322; 95% CI: 1.195−1.464) compared with the normal BMI category. Among the HNC cases, the incidence rates of laryngeal (HR: 1.3; 95% CI: 1.085−1.558), oral cavity (HR: 1.277; 95% CI: 1.011−1.611), and oropharyngeal (HR: 1.584; 95% CI: 1.25−2.008) cancers were higher in the low BMI category compared with the normal BMI category. No significant association was detected between low BMI and sinus cancer, salivary gland cancer, or nasopharyngeal cancer. The low WC category (<80 cm in men and <75 cm in women) was related to a risk of hypopharyngeal (HR: 1.268; 95% CI: 1.061−1.514) and laryngeal (HR: 1.118; 95% CI: 1.007−1.241) cancers. The HR for occurrence of HNC was high in underweight participants according to smoking status (1.219 for never smoker vs. 1.448 for ever smoker, p for interaction = 0.0015) and drinking status (1.193 for never drinker vs. 1.448 for ever drinker, p for interaction = 0.0044). Conclusions: Low BMI was associated with the risk of some types of HNC. The results of this study could assist etiological investigations and prevention strategies.

Indexed as

body mass indexepidemiologyhead and neck neoplasmsKoreawaist circumference

Identifiers

PMID36010881
PMCPMC9405652
OpenAlexW4290999620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.