ArticleFoods (Basel, Switzerland)2022
Extracts of Common Vegetables Inhibit the Growth of Ovary Cancer Cells.
Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Effect of Thermal Treatment on the Antiproliferative and Antioxidant Activities of Garlic.Food science & nutrition · 2025Article
- Improving the Value Utilization of Tuna Peptide Powder for the Cosmetics Field Through Ozone Oxidation.Marine drugs · 2025Article
- Unraveling the role of long non-coding RNAs in therapeutic resistance in acute myeloid leukemia: New prospects & challenges.Non-coding RNA research · 2024Review
- Which Constituents Determine the Antioxidant Activity and Cytotoxicity of Garlic? Role of Organosulfur Compounds and Phenolics.International journal of molecular sciences · 2024Article
- Comparison of Antioxidant and Antiproliferative Effects of Various Forms of Garlic and Ramsons.Molecules (Basel, Switzerland) · 2023Article
- Antioxidant and Antiproliferative Activities of Kale (Molecules (Basel, Switzerland) · 2023Article
- Experimental Study of Garlic Root Cutting Based on Deep Learning Application in Food Primary Processing.Foods (Basel, Switzerland) · 2022Article
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Authors and funding
4 authors.
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Abstract
There is recent interest in a diet that can be recommended for patients suffering from cancer. In this respect, the effects were studied of the extracts of several common fruits, herbs and vegetables on the viability of two human ovary cancer cell lines (SKOV-3 and PEO1) in vitro. Normal human MRC-5 fibroblasts were used as a control cell line. The extracts of garlic, horseradish and curly kale as well as green and black tea were the most effective in lowering the viability of ovarian cancer cells, while not affecting the viability of MRC-5 fibroblasts. Except for garlic and horseradish, the cytotoxic effects of the extracts correlated with their polyphenol content. The examination of changes in the content of ATP and glutathione, in the level of reactive oxygen species, mitochondrial potential and mitochondrial mass did not show a consistent pattern, suggesting that various extracts may act via different mechanisms. Although the extracts' toxicity to cells in vitro is a first and direct suggestion concerning their possible anticancer effects in vivo, these results point to potential vegetable candidates to become diet components recommended for ovary cancer patients.
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