Evidence map›Paper›PMID 36010438›Full record

ReviewFoods (Basel, Switzerland)2022

Synbiotics and Gut Microbiota: New Perspectives in the Treatment of Type 2 Diabetes Mellitus.

Haoran Jiang, Miaomiao Cai, Boyuan Shen, Qiong Wang, Tongcun Zhang, Xiang Zhou

Open access · goldAbstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. PeerJ · 2025
    Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Gut microbiota microbial metabolites in diabetic nephropathy patients: far to go.Frontiers in cellular and infection microbiology · 2024
    Review
  19. Article
  20. Benefits of CombiningFoods (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Haoran JiangCollege of Life Sciences & Health, Wuhan University of Science & Technology, Wuhan 430065, China.ORCID 0000-0002-5396-1089
Miaomiao CaiCollege of Life Sciences & Health, Wuhan University of Science & Technology, Wuhan 430065, China.
Boyuan ShenCollege of Life Sciences & Health, Wuhan University of Science & Technology, Wuhan 430065, China.
Qiong WangCollege of Life Sciences & Health, Wuhan University of Science & Technology, Wuhan 430065, China.
Tongcun ZhangCollege of Life Sciences & Health, Wuhan University of Science & Technology, Wuhan 430065, China.
Xiang ZhouCollege of Life Sciences & Health, Wuhan University of Science & Technology, Wuhan 430065, China.
Wuhan University of Science and Technology · CN

Funding

Ministry of Science and Technology of the People's Republic of China 2017YFD0400300
6 · The paper itself

Abstract

The number of people with type 2 diabetes mellitus (T2DM) has increased sharply over the past decades. Apart from genetic predisposition, which may cause some of the diagnosed cases, an unhealthy diet and lifestyle are incentive triggers of this global epidemic. Consumption of probiotics and prebiotics to gain health benefits has become increasingly accepted by the public in recent years, and their critical roles in alleviating T2DM symptoms are confirmed by accumulating studies. Microbiome research reveals gut colonization by probiotics and their impacts on the host, while oral intake of prebiotics may stimulate existing metabolisms in the colon. The use of synbiotics (a combination of prebiotics and probiotics) can thus show a synergistic effect on T2DM through modulating the gastrointestinal microenvironment. This review summarizes the research progress in the treatment of T2DM from the perspective of synbiotics and gut microbiota and provides a class of synbiotics which are composed of lactulose, arabinose, and

Indexed as

gut microbiotaLactobacillus plantarumsynbioticstype 2 diabetes mellitus

Identifiers

PMID36010438
PMCPMC9407597
OpenAlexW4291464599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.