Evidence map›Paper›PMID 36010288›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Application of A U-Net for Map-like Segmentation and Classification of Discontinuous Fibrosis Distribution in Gd-EOB-DTPA-Enhanced Liver MRI.

Quirin David Strotzer, Hinrich Winther, Kirsten Utpatel, Alexander Scheiter, Claudia Fellner, Michael Christian Doppler, Kristina Imeen Ringe, Florian Raab, Michael Haimerl, Wibke Uller and 3 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Quirin David StrotzerDepartment of Diagnostic and Interventional Radiology, University Hospital Regensburg, 93053 Regensburg, Germany.ORCID 0000-0001-9093-2589
Hinrich WintherDepartment of Diagnostic and Interventional Radiology, Hannover University Medical Center, 30625 Hannover, Germany.
Kirsten UtpatelInstitute of Pathology, University of Regensburg, 93053 Regensburg, Germany.
Alexander ScheiterInstitute of Pathology, University of Regensburg, 93053 Regensburg, Germany.ORCID 0000-0001-6734-261X
Claudia FellnerDepartment of Diagnostic and Interventional Radiology, University Hospital Regensburg, 93053 Regensburg, Germany.
Michael Christian DopplerDepartment of Diagnostic and Interventional Radiology, Medical Center University of Freiburg, 79106 Freiburg im Breisgau, Germany.
Kristina Imeen RingeDepartment of Diagnostic and Interventional Radiology, Hannover University Medical Center, 30625 Hannover, Germany.
Florian RaabDepartment of Diagnostic and Interventional Radiology, University Hospital Regensburg, 93053 Regensburg, Germany.
Michael HaimerlDepartment of Diagnostic and Interventional Radiology, University Hospital Regensburg, 93053 Regensburg, Germany.
Wibke UllerDepartment of Diagnostic and Interventional Radiology, Medical Center University of Freiburg, 79106 Freiburg im Breisgau, Germany.ORCID 0000-0001-6756-9005
Christian StroszczynskiDepartment of Diagnostic and Interventional Radiology, University Hospital Regensburg, 93053 Regensburg, Germany.
Lukas LuerkenDepartment of Diagnostic and Interventional Radiology, University Hospital Regensburg, 93053 Regensburg, Germany.
Niklas VerlohDepartment of Diagnostic and Interventional Radiology, Medical Center University of Freiburg, 79106 Freiburg im Breisgau, Germany.ORCID 0000-0002-8424-5827

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to evaluate whether U-shaped convolutional neuronal networks can be used to segment liver parenchyma and indicate the degree of liver fibrosis/cirrhosis at the voxel level using contrast-enhanced magnetic resonance imaging. This retrospective study included 112 examinations with histologically determined liver fibrosis/cirrhosis grade (Ishak score) as the ground truth. The T1-weighted volume-interpolated breath-hold examination sequences of native, arterial, late arterial, portal venous, and hepatobiliary phases were semi-automatically segmented and co-registered. The segmentations were assigned the corresponding Ishak score. In a nested cross-validation procedure, five models of a convolutional neural network with U-Net architecture (nnU-Net) were trained, with the dataset being divided into stratified training/validation (

Indexed as

Artificial Intelligencecirrhosisconvolutional neural networkliver fibrosissegmentationU-Net

Identifiers

PMID36010288
PMCPMC9406317

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.