Evidence map›Paper›PMID 36010149›Full record

ReviewChildren (Basel, Switzerland)2022

Antibiotherapy in Children with Cystic Fibrosis-An Extensive Review.

Ioana Mihaiela Ciuca, Mihaela Dediu, Diana Popin, Liviu Laurentiu Pop, Liviu Athos Tamas, Ciprian Nicolae Pilut, Bogdan Almajan Guta, Zoran Laurentiu Popa

Open access · goldAbstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Extracellular vesicles secreted by primary human bronchial epithelial cells reduceAmerican journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. "Unraveling the Clot-Miscarriage Nexus: Mechanisms, Management, and Future Directions in Thrombosis-Related Recurrent Pregnancy Loss".Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ioana Mihaiela CiucaPediatric Department, University of Medicine and Pharmacy "Victor Babes" Timisoara, 2 Eftimie Murgu Square, 300041 Timisoara, Romania.ORCID 0000-0002-2879-8080
Mihaela DediuPediatric Department, University of Medicine and Pharmacy "Victor Babes" Timisoara, 2 Eftimie Murgu Square, 300041 Timisoara, Romania.ORCID 0000-0002-8085-4406
Diana PopinPediatric Pulmonology Unit, Clinical County Hospital Timisoara, Evlia Celebi 1-3, 300226 Timisoara, Romania.
Liviu Laurentiu PopPediatric Department, University of Medicine and Pharmacy "Victor Babes" Timisoara, 2 Eftimie Murgu Square, 300041 Timisoara, Romania.
Liviu Athos TamasBiochemistry Department, University of Medicine and Pharmacy "Victor Babes" Timisoara, 2 Eftimie Murgu Square, 300041 Timisoara, Romania.
Ciprian Nicolae PilutMicrobiology Department, University of Medicine and Pharmacy "Victor Babes" Timisoara, 2 Eftimie Murgu Square, 300041 Timisoara, Romania.
Bogdan Almajan GutaKinesiotherapy and Special Motricity Department, West University of Timisoara, 4 Vasile Parvan bld., 300223 Timisoara, Romania.
Zoran Laurentiu PopaDepartment of Obstetrics and Gynecology, University of Medicine and Pharmacy "Victor Babes" Timisoara, 2 Eftimie Murgu Square, 300041 Timisoara, Romania.
Victor Babeș University of Medicine and Pharmacy Timișoara · ROWest University of Timişoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In cystic fibrosis (CF), the respiratory disease is the main factor that influences the outcome and the prognosis of patients, bacterial infections being responsible for severe exacerbations. The etiology is often multi-microbial and with resistant strains. The aim of this paper is to present current existing antibiotherapy solutions for CF-associated infections in order to offer a reliable support for individual, targeted, and specific treatment. The inclusion criteria were studies about antibiotherapy in CF pediatric patients. Studies involving adult patients or those with only in vitro results were excluded. The information sources were all articles published until December 2021, in PubMed and ScienceDirect. A total of 74 studies were included, with a total number of 26,979 patients aged between 0-18 years. We approached each pathogen individual, with their specific treatment, comparing treatment solutions proposed by different studies. Preservation of lung function is the main goal of therapy in CF, because once parenchyma is lost, it cannot be recovered. Early personalized intervention and prevention of infection with reputable germs is of paramount importance, even if is an asymmetrical challenge. This research received no external funding.

Indexed as

antibioticsBurkholderia cepacian complexcystic fibrosispersonalized antibiotherapyPseudomonas aeruginosa

Identifiers

PMID36010149
PMCPMC9406924
OpenAlexW4293677845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.