Evidence map›Paper›PMID 36010101›Full record

ReviewChildren (Basel, Switzerland)2022

From Fetal to Neonatal Neuroimaging in TORCH Infections: A Pictorial Review.

Giulia Lucignani, Alessia Guarnera, Maria Camilla Rossi-Espagnet, Giulia Moltoni, Amanda Antonelli, Lorenzo Figà Talamanca, Chiara Carducci, Francesca Ippolita Calo Carducci, Antonio Napolitano, Carlo Gandolfo and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Frontal Paraventricular Cysts: Refined Definitions and Outcomes.AJNR. American journal of neuroradiology · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Macrocephaly and Finger Changes: A Narrative Review.International journal of molecular sciences · 2024
    Review
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Giulia Lucignani *Neuroradiology Unit, Imaging Department, Bambino Gesù Children's Hospital IRCCS, 00146 Rome, Italy.ORCID 0000-0002-1206-9991
Alessia Guarnera *Neuroradiology Unit, Imaging Department, Bambino Gesù Children's Hospital IRCCS, 00146 Rome, Italy.ORCID 0000-0001-5529-7575
Maria Camilla Rossi-EspagnetNeuroradiology Unit, Imaging Department, Bambino Gesù Children's Hospital IRCCS, 00146 Rome, Italy.
Giulia MoltoniNeuroradiology Unit, NESMOS Department, Sant'Andrea Hospital, La Sapienza University, 00146 Rome, Italy.
Amanda AntonelliNeuroradiology Unit, Imaging Department, Bambino Gesù Children's Hospital IRCCS, 00146 Rome, Italy.ORCID 0000-0001-6298-8593
Lorenzo Figà TalamancaNeuroradiology Unit, Imaging Department, Bambino Gesù Children's Hospital IRCCS, 00146 Rome, Italy.
Chiara CarducciNeuroradiology Unit, Imaging Department, Bambino Gesù Children's Hospital IRCCS, 00146 Rome, Italy.
Francesca Ippolita Calo CarducciAcademic Department of Paediatrics, Bambino Gesù Children's Hospital IRCCS, 00146 Rome, Italy.
Antonio NapolitanoMedical Physics Unit, Risk Management Enterprise, Bambino Gesù Children's Hospital IRCCS, 00146 Rome, Italy.
Carlo GandolfoNeuroradiology Unit, Imaging Department, Bambino Gesù Children's Hospital IRCCS, 00146 Rome, Italy.
Francesca CampiNeonatal Intensive Care Unit, Department of Medical and Surgical Neonatology, Bambino Gesù Children's Hospital IRCCS, 00146 Rome, Italy.
Cinzia AuritiNeonatal Intensive Care Unit, Department of Medical and Surgical Neonatology, Bambino Gesù Children's Hospital IRCCS, 00146 Rome, Italy.ORCID 0000-0001-9820-6557
Cecilia ParazziniDepartment of Pediatric Radiology and Neuroradiology, V. Buzzi Children's Hospital, Via Castelvetro 32, 20154 Milan, Italy.ORCID 0000-0003-0364-8673
Daniela LongoNeuroradiology Unit, Imaging Department, Bambino Gesù Children's Hospital IRCCS, 00146 Rome, Italy.
Bambino Gesù Children's Hospital · ITAzienda Ospedaliera Sant'Andrea · ITIRCCS Materno Infantile Burlo Garofolo · ITOspedale dei Bambini Vittore Buzzi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital infections represent a challenging and varied clinical scenario in which the brain is frequently involved. Therefore, fetal and neonatal neuro-imaging plays a pivotal role in reaching an accurate diagnosis and in predicting the clinical outcome. Congenital brain infections are characterized by various clinical manifestations, ranging from nearly asymptomatic diseases to syndromic disorders, often associated with severe neurological symptoms. Brain damage results from the complex interaction among the infectious agent, its specific cellular tropism, and the stage of development of the central nervous system at the time of the maternal infection. Therefore, neuroradiological findings vary widely and are the result of complex events. An early detection is essential to establishing a proper diagnosis and prognosis, and to guarantee an optimal and prompt therapeutic perinatal management. Recently, emerging infective agents (i.e., Zika virus and SARS-CoV2) have been related to possible pre- and perinatal brain damage, thus expanding the spectrum of congenital brain infections. The purpose of this pictorial review is to provide an overview of the current knowledge on fetal and neonatal brain neuroimaging patterns in congenital brain infections used in clinical practice.

Indexed as

CMVcongenital infectionfetal imagingMRIneonatal imagingSARS-CoV-2TORCH

Identifiers

PMID36010101
PMCPMC9406729
OpenAlexW4290973833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.