Evidence map›Paper›PMID 36010072›Full record

ArticleChildren (Basel, Switzerland)2022

Neonatal Cerebral Sinovenous Thrombosis and the Main Perinatal Risk Factors-A Retrospective Unicentric Study.

Catalina Filip, Gabriela Ildiko Zonda, Ingrid-Andrada Vasilache, Ioana Sadiye Scripcariu, Petronela Vicoveanu, Vlad Dima, Demetra Socolov, Luminita Paduraru

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. A Rare Cause of Neonatal Seizures-A Case Report.Journal of paediatrics and child health · 2025
    Article
  3. Article
  4. [Clinical characteristics and outcomes of 11 neonates with venous thrombosis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Catalina FilipSaint Spiridon University Hospital, Vascular Surgery Clinic, Independence Boulevard No. 1, 700111 Iasi, Romania.ORCID 0000-0002-2132-6742
Gabriela Ildiko ZondaDivision of Neonatology, Department of Mother and Child Care, "Grigore T. Popa" University of Medicine and Pharmacy, 700111 Iasi, Romania.ORCID 0000-0002-7206-4586
Ingrid-Andrada VasilacheDivision of Obstetrics and Gynecology, Department of Mother and Child Care, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-4718-392X
Ioana Sadiye ScripcariuDivision of Obstetrics and Gynecology, Department of Mother and Child Care, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Petronela VicoveanuDivision of Obstetrics and Gynecology, Department of Mother and Child Care, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Vlad DimaDepartment of Obstetrics, Gynecology and Neonatology, Filantropia Clinical Hospital, 11-13 Ion Mihalache Blv., Sector 1, 011171 Bucharest, Romania.
Demetra SocolovDivision of Obstetrics and Gynecology, Department of Mother and Child Care, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-0979-0200
Luminita PaduraruDivision of Neonatology, Department of Mother and Child Care, "Grigore T. Popa" University of Medicine and Pharmacy, 700111 Iasi, Romania.ORCID 0000-0002-3850-797X
Grigore T. Popa University of Medicine and Pharmacy · ROClinical Emergency Hospital Bucharest · ROSpitalul Clinic Judeţean de Urgenţe "Sf. Spiridon" Iaşi · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Neonatal cerebral sinovenous thrombosis (CSVT) is a rare disorder, associated with long-term neurological sequelae. The aim of this study was to retrospectively evaluate the most commonly encountered perinatal risk factors for this disease in a cohort of newborns from Romania. (2) Methods: The medical records of neonatal CSVT patients treated between January 2017 and December 2021 were descriptively assessed. (3) Results: The study included nine neonates, five males (55.56%) and four females (44.44%), who were born at term. The most commonly presented clinical manifestations were feeding difficulties, lethargy, respiratory distress, loss of consciousness, and seizures. Maternal-inherited thrombophilia, male sex, complicated delivery, perinatal asphyxia, and mechanical ventilation were frequently identified as potential risk factors for developing CSVT. The lesions were more frequently localized in the superior sagittal sinus (n = 7; 77.78%), followed by the transverse (n = 4; 44.44%), sigmoid (n = 2; 22.22%), and cavernous (n = 1; 11.11%) sinuses. Low-molecular-weight heparin was administered to all patients, and two of them died from thrombotic complications. (4) Conclusions: Recognition of potential risk factors and a prompt diagnosis of neonatal CSVT could lead to better patient management and to a reduction of severe complications.

Indexed as

cerebral sinovenous thrombosisinherited thrombophilianeonatalrisk factors

Identifiers

PMID36010072
PMCPMC9406898
OpenAlexW4290466087

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.