Evidence map›Paper›PMID 36009982›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Cerebrospinal Fluid System Infection in Children with Cancer: A Retrospective Analysis over 14 Years in a Major European Pediatric Cancer Center.

Antonia Diederichs, Evelyn Pawlik, Anke Barnbrock, Stefan Schöning, Jürgen Konczalla, Tobias Finger, Thomas Lehrnbecher, Stephan Göttig, Konrad Bochennek

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Antonia DiederichsDivision for Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, D-60596 Frankfurt, Germany.
Evelyn PawlikDivision for Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, D-60596 Frankfurt, Germany.
Anke BarnbrockDivision for Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, D-60596 Frankfurt, Germany.
Stefan SchöningDivision for Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, D-60596 Frankfurt, Germany.
Jürgen KonczallaDepartment of Neurosurgery, Johann Wolfgang Goethe-University, D-60596 Frankfurt, Germany.ORCID 0000-0001-9771-7806
Tobias FingerDepartment of Neurosurgery, Johann Wolfgang Goethe-University, D-60596 Frankfurt, Germany.
Thomas LehrnbecherDivision for Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, D-60596 Frankfurt, Germany.ORCID 0000-0002-6022-3439
Stephan GöttigInstitute for Medical Microbiology and Infection Control, Johann Wolfgang Goethe-University, D-60596 Frankfurt, Germany.ORCID 0000-0001-6896-5309
Konrad BochennekDivision for Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, D-60596 Frankfurt, Germany.ORCID 0000-0002-6881-6511
Goethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection of a cerebrospinal fluid system is a serious medical complication. We performed a retrospective monocentric analysis on temporary and permanent cerebrospinal fluid devices in children with and without cancer, covering a period of over 14 years. Between 2004 and 2017, 275 children with a cerebrospinal fluid system were seen at our institution. Thirty-eight children suffered from 51 microbiologically proven infectious episodes of the cerebrospinal fluid system (12 children with cancer and 26 children without cancer). Independently of the cerebrospinal fluid system used, the incidence of infection did not significantly differ between children with and without cancer and was the highest in children younger than one year. Infection occurred earlier in external ventricular drain (EVD) than ventriculoperitoneal (VP) shunt, and in EVD significantly earlier in children with cancer compared with patients without cancer. The pathogens isolated were mainly Gram-positive bacteria, in particular

Indexed as

cancercerebrospinal fluid systemchildhydrocephalusinfection

Identifiers

PMID36009982
PMCPMC9405352
OpenAlexW4292259522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.