Evidence map›Paper›PMID 36009970›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Comparative In Vitro Activity of Ceftolozane/Tazobactam against Clinical Isolates of

Juan Carlos García-Betancur, Elsa De La Cadena, María F Mojica, Cristhian Hernández-Gómez, Adriana Correa, Marcela A Radice, Paulo Castañeda-Méndez, Diego A Jaime-Villalon, Ana C Gales, José M Munita and 1 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 6 countries.

Juan Carlos García-BetancurGrupo de Investigación en Resistencia Antimicrobiana y Epidemiología Hospitalaria, Universidad El Bosque, Bogotá 110121, Colombia.ORCID 0000-0001-5569-6031
Elsa De La CadenaGrupo de Investigación en Resistencia Antimicrobiana y Epidemiología Hospitalaria, Universidad El Bosque, Bogotá 110121, Colombia.ORCID 0000-0003-0361-7893
María F MojicaGrupo de Investigación en Resistencia Antimicrobiana y Epidemiología Hospitalaria, Universidad El Bosque, Bogotá 110121, Colombia.ORCID 0000-0002-1380-9824
Cristhian Hernández-GómezGrupo de Investigación en Resistencia Antimicrobiana y Epidemiología Hospitalaria, Universidad El Bosque, Bogotá 110121, Colombia.
Adriana CorreaClínica Imbanaco, Cali 760031, Colombia.
Marcela A RadiceLaboratorio de Resistencia Bacteriana, Facultad de Farmacia y Bioquímica, IBaViM, Universidad de Buenos Aires, Buenos Aires 70512, Argentina.
Paulo Castañeda-MéndezHospital Médica Sur, Ciudad de México 14050, Mexico.ORCID 0000-0003-4460-9937
Diego A Jaime-VillalonHospital Médica Sur, Ciudad de México 14050, Mexico.
Ana C GalesDepartment of Internal Medicine, Division of Infectious Diseases, Universidade Federal de São Paulo, São Paulo 04039-032, Brazil.
José M MunitaMillennium Initiative for Collaborative Research on Bacterial Resistance (MICROB-R), Santiago 7650568, Chile.ORCID 0000-0002-7870-1056
María Virginia VillegasGrupo de Investigación en Resistencia Antimicrobiana y Epidemiología Hospitalaria, Universidad El Bosque, Bogotá 110121, Colombia.ORCID 0000-0003-1898-9067
Universidad El Bosque · COHospital Médica Sur · MXConsejo Nacional de Investigaciones Científicas y Técnicas · ARUniversidad del Desarrollo · CLUniversidade Federal de São Paulo · BRUniversidad Santiago de Cali · CO

Funding

Merck Sharp & Dohme (MSD) 10020230
6 · The paper itself

Abstract

backgroundCeftolozane/tazobactam (C/T) is a combination of an antipseudomonal oxyiminoaminothiazolyl cephalosporin with potent in vitro activity against

methodsa total of 2760 clinical isolates (508

resultsaccording to the CLSI breakpoints, 68.1% (346/508) of

conclusionsthese results show that C/T is an active β-lactam agent against clinical isolates of

Indexed as

antimicrobial resistanceceftolozane/tazobactamEnterobacteralesLatin AmericaPseudomonas aeruginosa

Identifiers

PMID36009970
PMCPMC9405202
OpenAlexW4291414680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.