Evidence map›Paper›PMID 36009861›Full record

ArticleBiology2022

Hypoxia Affects HIF-1/LDH-A Signaling Pathway by Methylation Modification and Transcriptional Regulation in Japanese Flounder (

Binghua Liu, Haishen Wen, Jun Yang, Xiaohui Li, Guangling Li, Jingru Zhang, Shuxian Wu, Ian Ae Butts, Feng He

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 citations in OpenAlex.

  1. Physiological and Pathological Responses of Grass Carp (Animals : an open access journal from MDPI · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Binghua LiuKey Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266000, China.
Haishen WenKey Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266000, China.
Jun YangKey Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266000, China.
Xiaohui LiKey Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266000, China.
Guangling LiKey Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266000, China.
Jingru ZhangKey Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266000, China.
Shuxian WuKey Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266000, China.
Ian Ae ButtsSchool of Fisheries, Aquaculture and Aquatic Sciences, Auburn University, Auburn, AL 36849, USA.
Feng HeKey Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266000, China.
Ocean University of China · CNAuburn University · US

Funding

National Natural Science Foundation of China 31672642Natural Science Foundation of Shandong Province, China ZR2014CM018Ocean University of China-Auburn University (OUC-AU) Grants program 202010USDA National Institute of Food and Agriculture Hatch project 1013854
6 · The paper itself

Abstract

Japanese flounder (

Indexed as

epigenetic modificationhypoxia stressJapanese flounderphysiological responsetranscriptional regulation

Identifiers

PMID36009861
PMCPMC9405012
OpenAlexW4293777667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.