Evidence map›Paper›PMID 36009837›Full record

ArticleBiology2022

Innovative Hybrid-Alignment Annotation Method for Bioinformatics Identification and Functional Verification of a Novel Nitric Oxide Synthase in

Hung-Che Lin, Hao-Ai Shui, Kuo-Yang Huang, Wei-Zhi Lin, Hsin-Yi Chang, Hwei-Jen Lee, Ying-Chih Lin, Yuahn-Sieh Huang, Guan-Ru Chen, Ya-Ting Yang and 9 more

Open access · goldAbstract read
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Hung-Che LinGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0002-0138-1904
Hao-Ai ShuiGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.
Kuo-Yang HuangGraduate Institute of Pathology and Parasitology, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0002-4038-1579
Wei-Zhi LinGraduate Institute of Life Sciences, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0002-7121-2380
Hsin-Yi ChangGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0002-2742-0676
Hwei-Jen LeeDepartment of Biochemistry, National Defense Medical Center, Taipei 114, Taiwan.
Ying-Chih LinSchool of Public Health, National Defense Medical Center, Taipei 114, Taiwan.
Yuahn-Sieh HuangGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0003-3527-6421
Guan-Ru ChenSchool of Public Health, National Defense Medical Center, Taipei 114, Taiwan.
Ya-Ting YangSchool of Public Health, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0001-5880-4827
Hsiu-Lin LiuSchool of Public Health, National Defense Medical Center, Taipei 114, Taiwan.
Yi-Syuan WuGraduate Institute of Life Sciences, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0001-9609-6489
Chia-Shiang ChengGraduate Institute of Life Sciences, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0002-2298-8000
Ching-Lung KoGraduate Institute of Life Sciences, National Defense Medical Center, Taipei 114, Taiwan.
Yu-Tien ChangSchool of Public Health, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0002-1801-7041
Jih-Chin LeeGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.
Chen-Shien LinChinese Medicine Department, Taipei Hospital, Ministry of Health and Welfare, New Taipei City 242, Taiwan.
Chih-Hung WangGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0001-5058-4356
Chi-Ming ChuGraduate Institute of Medical Sciences, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0001-8563-1378
National Defense Medical Center · TWTri-Service General Hospital · TWFu Jen Catholic University · TWMinistry of Health and Welfare · TW

Funding

Tri-Service General Hospital TSGH-C108-198, TSGH-E-110266
6 · The paper itself

Abstract

Both the annotation and identification of genes in pathogenic parasites are still challenging. Although, as a survival factor, nitric oxide (NO) has been proven to be synthesized in

Indexed as

bioinformaticgene annotationnovel nitric oxide synthaseprotein structure predictionTrichomonas vaginalis

Identifiers

PMID36009837
PMCPMC9404748
OpenAlexW4291415360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.