Evidence map›Paper›PMID 36009773›Full record

ReviewBiology2022

Microalgae-Based Biorefineries: Challenges and Future Trends to Produce Carbohydrate Enriched Biomass, High-Added Value Products and Bioactive Compounds.

Eugenia J Olguín, Gloria Sánchez-Galván, Imilla I Arias-Olguín, Francisco J Melo, Ricardo E González-Portela, Lourdes Cruz, Roberto De Philippis, Alessandra Adessi

Abstract readReview
In one paragraph

Review in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. A Low-DimensionalMolecules (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Cascade Biorefinery ofACS sustainable chemistry & engineering · 2026
    Article
  4. Toward Industrial Application of Cyanobacterial Biosorption: Insights From Real Electroplating Effluents.Water environment research : a research publication of the Water Environment Federation · 2026
    Article
  5. Review
  6. Integrated algal systems for industrial COArchives of microbiology · 2026
    Review
  7. Review
  8. Article
  9. Review
  10. Valorization ofMarine drugs · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Plant Biostimulants to Enhance Abiotic Stress Resilience in Crops.International journal of molecular sciences · 2025
    Review
  16. Applications of the MicroalgaeLife (Basel, Switzerland) · 2024
    Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eugenia J OlguínEnvironmental Biotechnology Group, Biotechnological Management of Resources Network, Institute of Ecology (INECOL), Xalapa, Veracruz 91073, Mexico.ORCID 0000-0001-6906-2750
Gloria Sánchez-GalvánEnvironmental Biotechnology Group, Biotechnological Management of Resources Network, Institute of Ecology (INECOL), Xalapa, Veracruz 91073, Mexico.
Imilla I Arias-OlguínInternational Centre for Clean Technologies and Sustainable Development, (CITELDES, A.C.), Xalapa, Veracruz 91190, Mexico.
Francisco J MeloEnvironmental Biotechnology Group, Biotechnological Management of Resources Network, Institute of Ecology (INECOL), Xalapa, Veracruz 91073, Mexico.
Ricardo E González-PortelaEnvironmental Biotechnology Group, Biotechnological Management of Resources Network, Institute of Ecology (INECOL), Xalapa, Veracruz 91073, Mexico.
Lourdes CruzEnvironmental Biotechnology Group, Biotechnological Management of Resources Network, Institute of Ecology (INECOL), Xalapa, Veracruz 91073, Mexico.
Roberto De PhilippisDepartment of Agriculture Food Environment & Forestry (DAGRI), University of Florence, 50144 Florence, Italy.ORCID 0000-0001-7398-3536
Alessandra AdessiDepartment of Agriculture Food Environment & Forestry (DAGRI), University of Florence, 50144 Florence, Italy.ORCID 0000-0002-6144-644X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microalgae have demonstrated a large potential in biotechnology as a source of various macromolecules (proteins, carbohydrates, and lipids) and high-added value products (pigments, poly-unsaturated fatty acids, peptides, exo-polysaccharides, etc.). The production of biomass at a large scale becomes more economically feasible when it is part of a biorefinery designed within the circular economy concept. Thus, the aim of this critical review is to highlight and discuss challenges and future trends related to the multi-product microalgae-based biorefineries, including both phototrophic and mixotrophic cultures treating wastewater and the recovery of biomass as a source of valuable macromolecules and high-added and low-value products (biofertilizers and biostimulants). The therapeutic properties of some microalgae-bioactive compounds are also discussed. Novel trends such as the screening of species for antimicrobial compounds, the production of bioplastics using wastewater, the circular economy strategy, and the need for more Life Cycle Assessment studies (LCA) are suggested as some of the future research lines.

Indexed as

bioactive compoundcircular economymixotrophic culturesmulti-product biorefineriesthird-generation biorefinerieswastewater

Identifiers

PMID36009773
PMCPMC9405046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.