Evidence map›Paper›PMID 36009745›Full record

ReviewAnimals : an open access journal from MDPI2022

Yeast β-Glucans as Fish Immunomodulators: A Review.

Cristian Machuca, Yuniel Méndez-Martínez, Martha Reyes-Becerril, Carlos Angulo

Open access · goldAbstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Effects of DietaryBiology · 2025
    Article
  14. Dietary Supplementation withAnimals : an open access journal from MDPI · 2025
    Article
  15. Article
  16. Article
  17. Brewers' Yeast (Aquaculture nutrition · 2025
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Cristian MachucaImmunology & Vaccinology Group, Centro de Investigaciones Biológicas del Noroeste (CIBNOR), Instituto Politécnico Nacional 195, Playa Palo de Santa Rita Sur, La Paz 23096, Mexico.
Yuniel Méndez-MartínezFacultad de Ciencias Pecuarias, Universidad Técnica Estatal de Quevedo (UTEQ), Quevedo 120301, Ecuador.ORCID 0000-0002-5365-5794
Martha Reyes-BecerrilImmunology & Vaccinology Group, Centro de Investigaciones Biológicas del Noroeste (CIBNOR), Instituto Politécnico Nacional 195, Playa Palo de Santa Rita Sur, La Paz 23096, Mexico.
Carlos AnguloImmunology & Vaccinology Group, Centro de Investigaciones Biológicas del Noroeste (CIBNOR), Instituto Politécnico Nacional 195, Playa Palo de Santa Rita Sur, La Paz 23096, Mexico.ORCID 0000-0002-7965-1679
Instituto Politécnico Nacional · MXUniversidad Técnica Estatal de Quevedo · EC

Funding

Consejo Nacional de Ciencia y Tecnología PDCPN2014-01/248033)
6 · The paper itself

Abstract

Administration of immunostimulants in fish is a preventive method to combat infections. A wide variety of these biological molecules exist, among which one of the yeast wall compounds stands out for its different biological activities. The β-glucan that forms the structural part of yeast is capable of generating immune activity in fish by cell receptor recognition. The most frequently used β-glucans for the study of mechanisms of action are those of commercial origin, with doses recommended by the manufacturer. Nevertheless, their immune activity is inefficient in some fish species, and increasing the dose may show adverse effects, including immunosuppression. Conversely, experimental β-glucans from other yeast species show different activities, such as antibacterial, antioxidant, healing, and stress tolerance properties. Therefore, this review analyses the most recent scientific reports on the use of yeast β-glucans in freshwater and marine fish.

Indexed as

biomoleculesfunctional carbohydratesimmunityinfectious diseases

Identifiers

PMID36009745
PMCPMC9405025
OpenAlexW4293053096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.