ArticleAnimals : an open access journal from MDPI2022
Identification of Genes Associated with Crest Cushion Development in the Chinese Crested Duck.
Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors at 1 institution in 1 country.
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Abstract
The crest trait is a specific and widely distributed phenotype in birds. However, the shape and function vary in different species of birds. To understand the mechanism of crest formation, the present study used RNA sequencing and weighted gene co-expression network analysis (WGCNA) to identify the crest-cushion-associated genes in the Chinese crested (CC) duck. As a result, 28, 40, 32, 33, and 126 differentially expressed genes (DEGs) were identified between CC and cherry valley (CV) ducks at the embryonic days (E)15, E22, E28, D7 (7 days old), and D42 stages, respectively. In addition, the results of WGCNA show that 3697 (turquoise module), 485 (green-yellow module), 687 (brown module), 205 (red module), and 1070 (yellow module) hub genes were identified in the E15, E22, E28, D7, and D42 stages, respectively. Based on the results of DEGs and WGCNA Venn analysis, three, two, zero, one, and seven genes were found to be associated with crest cushion formation at the E15, E22, E28, D7, and D42 stages, respectively. The expression of all the associated genes and some DEGs was verified by real-time quantitative polymerase chain reaction. In conclusion, this study provided an approach revealing the molecular mechanisms underlying the crested trait development.
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