Evidence map›Paper›PMID 36009622›Full record

ArticleAnimals : an open access journal from MDPI2022

Immunohistochemical Distribution of Serotonin Transporter (SERT) in the Optic Lobe of the Honeybee,

Cristiano Bombardi, Giulia Salamanca, Claudio Tagliavia, Annamaria Grandis, Fanny Mille, Maria Grazia De Iorio, Giulietta Minozzi

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Insects · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Cristiano BombardiDepartment of Veterinary Medical Sciences, University of Bologna, Via Tolara di Sopra, 50, Ozzano dell'Emilia, 40064 Bologna, Italy.ORCID 0000-0002-5685-1977
Giulia SalamancaDepartment of Veterinary Medical Sciences, University of Bologna, Via Tolara di Sopra, 50, Ozzano dell'Emilia, 40064 Bologna, Italy.ORCID 0000-0003-4322-0030
Claudio TagliaviaDepartment of Veterinary Medical Sciences, University of Bologna, Via Tolara di Sopra, 50, Ozzano dell'Emilia, 40064 Bologna, Italy.ORCID 0000-0002-8628-693X
Annamaria GrandisDepartment of Veterinary Medical Sciences, University of Bologna, Via Tolara di Sopra, 50, Ozzano dell'Emilia, 40064 Bologna, Italy.
Fanny MilleDepartment of Veterinary Medical Sciences, University of Bologna, Via Tolara di Sopra, 50, Ozzano dell'Emilia, 40064 Bologna, Italy.ORCID 0000-0002-3555-9379
Maria Grazia De IorioDepartment of Veterinary Medicine and Animal Sciences, University of Milan, 26900 Lodi, Italy.
Giulietta MinozziDepartment of Veterinary Medicine and Animal Sciences, University of Milan, 26900 Lodi, Italy.ORCID 0000-0002-0020-8798
University of Bologna · ITUniversity of Milan · IT

Funding

Lombardy Region (FEASR program), PSR 2014-2020 - BEENOMIX 1.0 Project 2016/00361532 / G42F16000540002Lombardy Region (FEASR program), PSR 2014-2020 - BEENOMIX 2.0 project 201801057971/G44I19001910002
6 · The paper itself

Abstract

Visual information is processed in the optic lobes, which consist of three retinotopic neuropils. These are the lamina, the medulla and the lobula. Biogenic amines play a crucial role in the control of insect responsiveness, and serotonin is clearly related to aggressiveness in invertebrates. Previous studies suggest that serotonin modulates aggression-related behaviours, possibly via alterations in optic lobe activity. The aim of this investigation was to immunohistochemically localize the distribution of serotonin transporter (SERT) in the optic lobe of moderate, docile and aggressive worker honeybees. SERT-immunoreactive fibres showed a wide distribution in the lamina, medulla and lobula; interestingly, the highest percentage of SERT immunoreactivity was observed across all the visual neuropils of the docile group. Although future research is needed to determine the relationship between the distribution of serotonin fibres in the honeybee brain and aggressive behaviours, our immunohistochemical study provides an anatomical basis supporting the role of serotonin in aggressive behaviour in the honeybee

Indexed as

honeybeelaminalobulamedullaoptic lobeserotoninSERT

Identifiers

PMID36009622
PMCPMC9404419
OpenAlexW4292506078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.