ArticleBiomedicines2022
Machine Learning Data Analysis Highlights the Role of
Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 48 citations in OpenAlex.
- A data-driven universal gut microbiome health assessment: a machine learning framework trained on large metagenomic data.Frontiers in microbiology · 2026Article
- Phylo-Spec: a phylogeny-fusion deep learning model advances microbiome status identification.mSystems · 2025Article
- Identifying gut microbiota composition disparities in autistic individuals and their unaffected siblings: correlations with clinical characteristics.Translational psychiatry · 2025Article
- Causal relationship between gut microbiota, metabolites, and short stature: a Mendelian randomization study.Pediatric research · 2025Article
- Causal Association Between Oral Microbiota and Major Salivary Gland Cancer: A Bidirectional Two-Sample Mendelian Randomization Study.Oral health & preventive dentistry · 2025Article
- Distinct gut microbiota profiles in acute vs. chronic sinusitis: potential biomarkers.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Integrating 16S rRNA Gene Sequencing and Metabolomics Analysis to Reveal the Mechanism of L-Proline in Preventing Autism-like Behavior in Mice.Nutrients · 2025Article
- Microalgae-based bacteria for oral treatment of ASD through enhanced intestinal colonization and homeostasis.Theranostics · 2025Article
- Preliminary analysis of salivary microbiota in catathrenia (nocturnal groaning) using machine learning algorithms.Journal of oral microbiology · 2025Article
- Annexin A1 levels affect microbiota in health and DSS-induced colitis/inflammatory bowel disease development.Frontiers in immunology · 2025Article
- Correction of Batch Effect in Gut Microbiota Profiling of ASD Cohorts from Different Geographical Origins.Biomedicines · 2024Article
- Contributions of Artificial Intelligence to Analysis of Gut Microbiota in Autism Spectrum Disorder: A Systematic Review.Children (Basel, Switzerland) · 2024Review
- Autism spectrum disorders and the gastrointestinal tract: insights into mechanisms and clinical relevance.Nature reviews. Gastroenterology & hepatology · 2024Review
- A robust microbiome signature for autism spectrum disorder across different studies using machine learning.Scientific reports · 2024Article
- A comprehensive overview of microbiome data in the light of machine learning applications: categorization, accessibility, and future directions.Frontiers in microbiology · 2024Review
- Correlation between gut microbiota composition, enteric infections and linear growth impairment: a case-control study in childhood stunting in Pidie, Aceh, Indonesia.Gut pathogens · 2023Article
- Alteration of the Gut Microbiota in Pigs Infected with African Swine Fever Virus.Veterinary sciences · 2023Article
- Systematic bibliometric and visualized analysis of research hotspots and trends in artificial intelligence in autism spectrum disorder.Frontiers in neuroinformatics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 1 country.
Funding
Abstract
In recent years, the involvement of the gut microbiota in disease and health has been investigated by sequencing the 16S gene from fecal samples. Dysbiotic gut microbiota was also observed in Autism Spectrum Disorder (ASD), a neurodevelopmental disorder characterized by gastrointestinal symptoms. However, despite the relevant number of studies, it is still difficult to identify a typical dysbiotic profile in ASD patients. The discrepancies among these studies are due to technical factors (i.e., experimental procedures) and external parameters (i.e., dietary habits). In this paper, we collected 959 samples from eight available projects (540 ASD and 419 Healthy Controls, HC) and reduced the observed bias among studies. Then, we applied a Machine Learning (ML) approach to create a predictor able to discriminate between ASD and HC. We tested and optimized three algorithms: Random Forest, Support Vector Machine and Gradient Boosting Machine. All three algorithms confirmed the importance of five different genera, including
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.