Evidence map›Paper›PMID 36009547›Full record

ArticleBiomedicines2022

The Role of Adiponectin in the Resolution of Male-Obesity-Associated Secondary Hypogonadism after Metabolic Surgery and Its Impact on Cardiovascular Risk.

Pilar Cobeta, Roberto Pariente, Alvaro Osorio, Marta Marchan, Marta Cuadrado-Ayuso, David Pestaña, Julio Galindo, José I Botella-Carretero

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Pilar CobetaDepartment of Anesthesiology, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Roberto ParienteDepartment of Immunology, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Alvaro OsorioInstituto Ramón y Cajal de Investigación Sanitaria-IRyCIS, 28034 Madrid, Spain.
Marta MarchanDepartment of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Marta Cuadrado-AyusoInstituto Ramón y Cajal de Investigación Sanitaria-IRyCIS, 28034 Madrid, Spain.ORCID 0000-0001-6843-8322
David PestañaDepartment of Anesthesiology, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.
Julio GalindoInstituto Ramón y Cajal de Investigación Sanitaria-IRyCIS, 28034 Madrid, Spain.
José I Botella-CarreteroInstituto Ramón y Cajal de Investigación Sanitaria-IRyCIS, 28034 Madrid, Spain.ORCID 0000-0002-6425-2747
Instituto Ramón y Cajal de Investigación Sanitaria · ESHospital Universitario Ramón y Cajal · ES

Funding

Instituto de Salud Carlos III AES/ISCIII - PI18/00132
6 · The paper itself

Abstract

Male-obesity-associated secondary hypogonadism (MOSH) is a very prevalent entity that may resolve after marked weight loss. Adiponectin (APN) is an adipokine with anti-inflammatory properties that regulates metabolism. Low-circulating APN is associated with obesity, diabetes, and cardiovascular risk, along with circulating testosterone. We aimed to evaluate APN changes in men with MOSH (low circulating free testosterone (FT) with low or normal gonadotropins) and without it after metabolic surgery. We look for their possible association with cardiovascular risk measured by carotid intima-media thickness (cIMT). We included 60 men (20 submitted to lifestyle modification, 20 to sleeve gastrectomy, and 20 to gastric bypass) evaluated at baseline and 6 months after. The increase in APN at follow-up was reduction in patients with persistent MOSH (

Indexed as

adiponectincarotid intima-mediamale hypogonadismmetabolic surgeryobesitytestosterone

Identifiers

PMID36009547
PMCPMC9405896
OpenAlexW4292262815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.