Evidence map›Paper›PMID 36009338›Full record

ReviewAntioxidants (Basel, Switzerland)2022

The Potential Implications of Hydrogen Sulfide in Aging and Age-Related Diseases through the Lens of Mitohormesis.

Thi Thuy Tien Vo, Thao Duy Huynh, Ching-Shuen Wang, Kuei-Hung Lai, Zih-Chan Lin, Wei-Ning Lin, Yuh-Lien Chen, Tzu-Yu Peng, Ho-Cheng Wu, I-Ta Lee

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. CSE/HInternational journal of molecular sciences · 2025
    Review
  6. Roles of SIRT3 in aging and aging-related diseases.International journal of biological sciences · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Thi Thuy Tien VoSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 11031, Taiwan.
Thao Duy HuynhLab of Biomaterial, Department of Histology, Embryology, and Genetics, Pham Ngoc Thach University of Medicine, Ho Chi Minh City 72500, Vietnam.ORCID 0000-0001-5397-8000
Ching-Shuen WangSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0002-9771-8814
Kuei-Hung LaiPhD Program in Clinical Drug Development of Herbal Medicine, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0001-7220-6356
Zih-Chan LinDepartment of Nursing, Division of Basic Medical Sciences, and Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology, Puzi City, Chiayi County 61363, Taiwan.
Wei-Ning LinGraduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City 24205, Taiwan.ORCID 0000-0003-3205-871X
Yuh-Lien ChenDepartment of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei 10617, Taiwan.
Tzu-Yu PengSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0002-7168-9429
Ho-Cheng WuGraduate Institute of Pharmacognosy, College of Pharmacy, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0002-6648-6010
I-Ta LeeSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0002-8451-0280

Funding

Taipei Medical University Hospital 110TMUH-NE-03
6 · The paper itself

Abstract

The growing increases in the global life expectancy and the incidence of chronic diseases as a direct consequence have highlighted a demand to develop effective strategies for promoting the health of the aging population. Understanding conserved mechanisms of aging across species is believed helpful for the development of approaches to delay the progression of aging and the onset of age-related diseases. Mitochondrial hormesis (or mitohormesis), which can be defined as an evolutionary-based adaptive response to low-level stress, is emerging as a promising paradigm in the field of anti-aging. Depending on the severity of the perceived stress, there are varying levels of hormetic response existing in the mitochondria called mitochondrial stress response. Hydrogen sulfide (H

Indexed as

hydrogen sulfidemitochondrial dynamicsmitochondrial unfolded protein responsemitohormesismitophagy

Identifiers

PMID36009338
PMCPMC9404924

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.