Evidence map›Paper›PMID 36009270›Full record

ReviewAntioxidants (Basel, Switzerland)2022

Application of Response Surface Methodologies to Optimize High-Added Value Products Developments: Cosmetic Formulations as an Example.

Francisco-Javier Leyva-Jiménez, Álvaro Fernández-Ochoa, María de la Luz Cádiz-Gurrea, Jesús Lozano-Sánchez, Rodrigo Oliver-Simancas, M Elena Alañón, Ines Castangia, Antonio Segura-Carretero, David Arráez-Román

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Biotech (Basel (Switzerland)) · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francisco-Javier Leyva-JiménezDepartment of Analytical Chemistry and Food Science and Technology, University of Castilla-La Mancha, Ronda de Calatrava 7, 13071 Ciudad Real, Spain.ORCID 0000-0002-9589-7388
Álvaro Fernández-OchoaDepartment of Analytical Chemistry, Faculty of Sciences, University of Granada, Fuentenueva s/n, 18071 Granada, Spain.ORCID 0000-0001-5547-3209
María de la Luz Cádiz-GurreaDepartment of Analytical Chemistry, Faculty of Sciences, University of Granada, Fuentenueva s/n, 18071 Granada, Spain.ORCID 0000-0002-2613-4889
Jesús Lozano-SánchezDepartment of Food Science and Nutrition, Faculty of Pharmacy, University of Granada, Campus of Cartuja, 18071 Granada, Spain.ORCID 0000-0001-8769-3070
Rodrigo Oliver-SimancasDepartment of Analytical Chemistry and Food Science and Technology, University of Castilla-La Mancha, Ronda de Calatrava 7, 13071 Ciudad Real, Spain.ORCID 0000-0002-8313-2177
M Elena AlañónDepartment of Analytical Chemistry and Food Science and Technology, University of Castilla-La Mancha, Ronda de Calatrava 7, 13071 Ciudad Real, Spain.ORCID 0000-0002-5988-2947
Ines CastangiaDeparment of Scienze della Vita e dell'Ambiente, University of Cagliari, Via Ospedale 72, 09124 Cagliari, Italy.ORCID 0000-0002-3100-8107
Antonio Segura-CarreteroDepartment of Analytical Chemistry, Faculty of Sciences, University of Granada, Fuentenueva s/n, 18071 Granada, Spain.ORCID 0000-0002-5564-5338
David Arráez-RománDepartment of Analytical Chemistry, Faculty of Sciences, University of Granada, Fuentenueva s/n, 18071 Granada, Spain.ORCID 0000-0003-1267-6676

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, green and advanced extraction technologies have gained great interest to revalue several food by-products. This by-product revaluation is currently allowing the development of high value-added products, such as functional foods, nutraceuticals, or cosmeceuticals. Among the high valued-added products, cosmeceuticals are innovative cosmetic formulations which have incorporated bioactive natural ingredients providing multiple benefits on skin health. In this context, the extraction techniques are an important step during the elaboration of cosmetic ingredients since they represent the beginning of the formulation process and have a great influence on the quality of the final product. Indeed, these technologies are claimed as efficient methods to retrieve bioactive compounds from natural sources in terms of resource utilization, environmental impact, and costs. This review offers a summary of the most-used green and advanced methodologies to obtain cosmetic ingredients with the maximum performance of these extraction techniques. Response surface methodologies may be applied to enhance the optimization processes, providing a simple way to understand the extraction process as well as to reach the optimum conditions to increase the extraction efficiency. The combination of both assumes an economic improvement to attain high value products that may be applied to develop functional ingredients for cosmetics purposes.

Indexed as

cosmeceuticalsenzyme-assisted extractionexperimental designgreen technologiesmicrowave-assisted extractionphenolic compoundspressurized liquid extractionsupercritical fluid extractionultrasound-assisted extraction

Identifiers

PMID36009270
PMCPMC9404794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.