Evidence map›Paper›PMID 36009192›Full record

ArticleAntioxidants (Basel, Switzerland)2022

The Application of the Neuroprotective and Potential Antioxidant Effect of Ergotamine Mediated by Targeting N-Methyl-D-Aspartate Receptors.

Shinhui Lee, Sanung Eom, Khoa V A Nguyen, Jiwon Lee, Youngseo Park, Hye Duck Yeom, Junho H Lee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shinhui LeeDepartment of Biotechnology, Chonnam National University, Gwangju 61186, Korea.ORCID 0000-0002-5537-8241
Sanung EomDepartment of Biotechnology, Chonnam National University, Gwangju 61186, Korea.
Khoa V A NguyenDepartment of Biotechnology, Chonnam National University, Gwangju 61186, Korea.
Jiwon LeeDepartment of Biotechnology, Chonnam National University, Gwangju 61186, Korea.
Youngseo ParkDepartment of Biotechnology, Chonnam National University, Gwangju 61186, Korea.
Hye Duck YeomGoPath Laboratories, Buffalo Grove, IL 60089, USA.
Junho H LeeDepartment of Biotechnology, Chonnam National University, Gwangju 61186, Korea.ORCID 0000-0003-0913-8578
Chonnam National University · KR

Funding

National Research Foundation of Korea 2021R1A4A1031220National Research Foundation of Korea 2022R1A6A3A13068658
6 · The paper itself

Abstract

(1) Background: The N-methyl-D-aspartate receptors (NMDARs) mediate fast excitatory currents leading to depolarization. Postsynaptic NMDARs are ionotropic glutamate receptors that mediate excitatory glutamate or glycine signaling in the CNS and play a primary role in long-term potentiation, which is a major form of use-dependent synaptic plasticity. The overstimulation of NMDARs mediates excessive Ca

Indexed as

antioxidantergot alkaloidergotaminefree reactive oxygen speciesneuronal diseaseNMDAN-methyl-D-aspartatetwo-electrode voltage clamp

Identifiers

PMID36009192
PMCPMC9405237
OpenAlexW4288435344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.