Evidence map›Paper›PMID 36009111›Full record

ArticleBrain sciences2022

Prediction of Cognitive Degeneration in Parkinson's Disease Patients Using a Machine Learning Method.

Pei-Hao Chen, Ting-Yi Hou, Fang-Yu Cheng, Jin-Siang Shaw

Abstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pei-Hao ChenDepartment of Neurology, MacKay Memorial Hospital, Taipei 104217, Taiwan.ORCID 0000-0002-8391-3088
Ting-Yi HouInstitute of Mechatronic Engineering, National Taipei University of Technology, Taipei 106344, Taiwan.
Fang-Yu ChengInstitute of Long-Term Care, Mackay Medical College, New Taipei City 252, Taiwan.
Jin-Siang ShawInstitute of Mechatronic Engineering, National Taipei University of Technology, Taipei 106344, Taiwan.ORCID 0000-0002-8329-9452

Funding

Mackay Medical College MMH-MM-10811Mackay Memorial Hospital MMH-TT-10905National Taipei University of Technology NTUT-MMH-109-07
6 · The paper itself

Abstract

This study developed a predictive model for cognitive degeneration in patients with Parkinson's disease (PD) using a machine learning method. The clinical data, plasma biomarkers, and neuropsychological test results of patients with PD were collected and utilized as model predictors. Machine learning methods comprising support vector machines (SVMs) and principal component analysis (PCA) were applied to obtain a cognitive classification model. Using 32 comprehensive predictive parameters, the PCA-SVM classifier reached 92.3% accuracy and 0.929 area under the receiver operating characteristic curve (AUC). Furthermore, the accuracy could be increased to 100% and the AUC to 1.0 in a PCA-SVM model using only 13 carefully chosen features.

Indexed as

biomarkermachine learningneuropsychological testParkinson’s disease

Identifiers

PMID36009111
PMCPMC9405552

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.