Evidence map›Paper›PMID 36009107›Full record

ArticleBrain sciences2022

Robotic Verticalization plus Music Therapy in Chronic Disorders of Consciousness: Promising Results from a Pilot Study.

Rosaria De Luca, Mirjam Bonanno, Giuliana Vermiglio, Giovanni Trombetta, Ersilia Andidero, Angelo Caminiti, Patrizia Pollicino, Carmela Rifici, Rocco Salvatore Calabrò

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Rosaria De LucaIRCCS Centro Neurolesi Bonino Pulejo, Via Palermo, SS 113, C. da Casazza, 98124 Messina, Italy.
Mirjam BonannoIRCCS Centro Neurolesi Bonino Pulejo, Via Palermo, SS 113, C. da Casazza, 98124 Messina, Italy.
Giuliana VermiglioIRCCS Centro Neurolesi Bonino Pulejo, Via Palermo, SS 113, C. da Casazza, 98124 Messina, Italy.
Giovanni TrombettaIRCCS Centro Neurolesi Bonino Pulejo, Via Palermo, SS 113, C. da Casazza, 98124 Messina, Italy.
Ersilia AndideroIRCCS Centro Neurolesi Bonino Pulejo, Via Palermo, SS 113, C. da Casazza, 98124 Messina, Italy.
Angelo CaminitiIRCCS Centro Neurolesi Bonino Pulejo, Via Palermo, SS 113, C. da Casazza, 98124 Messina, Italy.
Patrizia PollicinoIRCCS Centro Neurolesi Bonino Pulejo, Via Palermo, SS 113, C. da Casazza, 98124 Messina, Italy.
Carmela RificiIRCCS Centro Neurolesi Bonino Pulejo, Via Palermo, SS 113, C. da Casazza, 98124 Messina, Italy.
Rocco Salvatore CalabròIRCCS Centro Neurolesi Bonino Pulejo, Via Palermo, SS 113, C. da Casazza, 98124 Messina, Italy.
Centro Neurolesi Bonino Pulejo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Music stimulation is considered a valuable form of intervention in disorders of consciousness (DoC); for instance, verticalization may improve motor and cognitive recovery. Our purpose is to investigate the effects of a novel rehabilitative approach combining robotic verticalization training (RVT) with personalized music stimulation in people with DoC. Methods: Sixteen subjects affected by minimally conscious state due to traumatic brain lesions who attended our Intensive Neuro-Rehabilitation Unit were enrolled in this randomized trial. They received either music robotic verticalization (MRV) using the Erigo device plus a personalized music playlist or only RVT without music stimuli. Each treatment was performed 2 times a week for 8 consecutive weeks in addition to standard neurorehabilitation. Results: We found significant improvements in all patients’ outcomes in the experimental group (who received MRV): Coma Recovery Scale-Revised (CRS-R) (p < 0.01), Level of Cognitive Functioning (LCF) (p < 0.02), Functional Independence Measure (FIM) (p < 0.03), Functional Communication Scale (FCS) (p < 0.007), Trunk Control Test (TCT) (p = 0.05). Significant differences between the two groups were also found in the main outcome measure CRS-R (p < 0.01) but not for TCT and FIM. Conclusions: Our study supports the safety and effectiveness of RVT with the Erigo device in chronic MCS, and the achievement of better outcomes when RVT is combined with music stimulation.

Indexed as

integrated strategic approachminimally conscious statemusic stimulationrobotic verticalization training

Identifiers

PMID36009107
PMCPMC9405818
OpenAlexW4290466977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.