Evidence map›Paper›PMID 36008997›Full record

ArticleBiomolecules2022

Toxicity Assessment of an Anti-Cancer Drug of p-Toluene Sulfonamide in Zebrafish Larvae Based on Cardiovascular and Locomotion Activities.

Andrew Yau Wah Young, Gilbert Audira, Ferry Saputra, Honeymae C Alos, Charlaine A Aventurado, Yu-Heng Lai, Ross D Vasquez, Chung-Der Hsiao, Chih-Hsin Hung

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Zebrafish live imaging: a strong weapon in anticancer drug discovery and development.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Andrew Yau Wah YoungInstitute of Biotechnology and Chemical Engineering, I-Shou University, Kaohsiung 84001, Taiwan.
Gilbert AudiraDepartment of Bioscience Technology, Chung Yuan Christian University, Chung-Li 320314, Taiwan.
Ferry SaputraDepartment of Bioscience Technology, Chung Yuan Christian University, Chung-Li 320314, Taiwan.ORCID 0000-0002-5715-9827
Honeymae C AlosThe Graduate School, University of Santo Tomas, Manila 1008, Philippines.
Charlaine A AventuradoThe Graduate School, University of Santo Tomas, Manila 1008, Philippines.
Yu-Heng LaiDepartment of Chemistry, Chinese Culture University, Taipei 11114, Taiwan.
Ross D VasquezDepartment of Pharmacy, Research Center for Natural and Applied Sciences, University of Santo Tomas, Manila 1008, Philippines.ORCID 0000-0002-5906-9710
Chung-Der HsiaoDepartment of Bioscience Technology, Chung Yuan Christian University, Chung-Li 320314, Taiwan.ORCID 0000-0002-6398-8672
Chih-Hsin HungInstitute of Biotechnology and Chemical Engineering, I-Shou University, Kaohsiung 84001, Taiwan.
Chung Yuan Christian University · TWUniversity of Santo Tomas · PHI-Shou University · TWChinese Culture University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

p-Toluene sulfonamide (p-TSA), a small molecular drug with antineoplastic activity is widely gaining interest from researchers because of its pharmacological activities. In this study, we explored the potential cardio and neural toxicity of p-TSA in sublethal concentrations by using zebrafish as an in vivo animal model. Based on the acute toxicity assay, the 96hr LC

Indexed as

Antineoplastic AgentsZebrafishAdenosine TriphosphatasesAnimalsHeartLarvaLocomotionMolecular Docking SimulationSulfonamidesTolueneAdenosine TriphosphatasesAntineoplastic AgentsSulfonamidesToluenecardiotoxicitylarvaneurotoxicityp-TSAzebrafish

Identifiers

PMID36008997
PMCPMC9405983
OpenAlexW4291015855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.