Evidence map›Paper›PMID 36008925›Full record

ArticleJournal of the International AIDS Society2022

Availability and experiences of differentiated antiretroviral therapy delivery at HIV care facilities in rural Zimbabwe: a mixed-method study.

Benedikt Christ, Janneke H van Dijk, Talent Y Nyandoro, Martina L Reichmuth, Cordelia Kunzekwenyika, Frédérique Chammartin, Matthias Egger, Alison Wringe, Marie Ballif, International epidemiology Databases to Evaluate AIDS in Southern Africa (IeDEA-SA)

Open access · goldAbstract read
In one paragraph

Article in Journal of the International AIDS Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Differentiated antiretroviral distribution: Implementation in five South African districts.African journal of primary health care & family medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 5 countries.

Benedikt ChristInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID 0000-0001-8478-9915
Janneke H van DijkSolidarMed, Masvingo, Zimbabwe.
Talent Y NyandoroSolidarMed, Masvingo, Zimbabwe.
Martina L ReichmuthInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Cordelia KunzekwenyikaSolidarMed, Masvingo, Zimbabwe.
Frédérique ChammartinInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Matthias EggerInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID 0000-0001-7462-5132
Alison WringeLondon School of Hygiene and Tropical Medicine, London, UK.ORCID 0000-0001-6939-3461
Marie BallifInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID 0000-0003-3133-3011
International epidemiology Databases to Evaluate AIDS in Southern Africa (IeDEA-SA)
University of Bern · CHGreat Zimbabwe University · ZWLondon School of Hygiene & Tropical Medicine · GB

Funding

Observational Antiretroviral Studies In Southern Africa (OASIS) CollaborationU01AI069924 · NIAID · UNIVERSITAT BERN · PI Cleophas Chimbetete, Mary-Ann Davies · 2006 to 2026
$55.9M
NIAID NIH HHS U01 AI069924
6 · The paper itself

Abstract

introductionZimbabwe adopted differentiated HIV care policies in 2015 to promote client-centred care and relieve strain on health facilities. We examined the availability, experiences and perceptions of differentiated antiretroviral therapy (ART) delivery in rural Zimbabwe following the policy adoption.

methodsWe undertook a cross-sectional mixed methods study in all the 26 facilities providing HIV care in a rural district in Zimbabwe. We collected quantitative data about ART delivery and visit durations from 31 healthcare providers and a purposive stratified sample of 378 clients obtaining ART either through routine care or differentiated ART delivery models. We performed 26 semi-structured interviews among healthcare providers and seven focus group discussions (FGDs) among clients to elicit their perceptions and experiences of ART delivery. Data were collected in 2019, with one follow-up FGD in 2021. We analysed the transcripts thematically, with inductive coding, to identify emerging themes.

resultsTwenty facilities (77%) offered at least one differentiated ART delivery models, including community ART refill groups (CARGs; 13 facilities, 50%), fast-track refill (8, 31%), family refill (6, 23%) or club refill (1, 4%). Thirteen facilities (50%) offered only one model. The median visit duration was 28 minutes (interquartile range [IQR]: 16-62). Participants in fast-track had the shortest visit durations (18 minutes, IQR: 11-24). Confidentiality and disclosure of HIV status, travelling long distances, travel costs and waiting times were the main issues influencing clients' views on differentiated ART delivery. Fast-track refill was perceived as the preferred model of clients for its limited involuntary disclosure and efficiency. In contrast, group- and community-based refill models reduced travel costs but were felt to be associated with involuntary disclosure of HIV status, which could discourage clients. Healthcare providers also experienced an additional workload when offering facility-based group models, such as CARGs.

conclusionsDifferentiated ART delivery models were widely available in this rural setting, but most facilities did not offer a choice of models to address clients' diverse preferences. A minority offered fast-track refills, although this model was often mentioned as desirable. Confidentiality, travel expenses and client waiting times are key elements to consider when planning and rolling out differentiated HIV care.

Indexed as

Anti-HIV AgentsHIV InfectionsCross-Sectional StudiesFocus GroupsHumansZimbabweAnti-HIV AgentsAfricaARTdifferentiated ART deliverydifferentiated careHIVZimbabwe

Identifiers

PMID36008925
PMCPMC9411726
OpenAlexW4293230252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.